How to manage weight with stage 3 melanoma?

Question

Hello doctor,

I am 52 with stage 3 melanoma and recently switched to a new treatment protocol. My oncologist is worried because I have gained almost 60 pounds since starting cancer treatment. A nurse mentioned compounded Semaglutide. Would it interfere with immunotherapy? How much weight could I lose monthly? What is the difference from Wegovy? I am worried about the side effects. My next round of treatment starts in 10 days, and I need to make a decision quickly. My mobility is getting worse.

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I can understand your concern.

A very small study found that Semaglutide increases the function of NK (natural killer), or natural killer cells, which squash cancer cells before they can grow into tumors. So, Semaglutide at least does not impair patient immunity.

Based on various studies and clinical trials, here is a quick snapshot-

First month: Average weight loss of approximately 7.59 pounds.
Three months: Average weight loss of roughly 18.23 pounds.
Six months: Average loss reaches about 32.83 pounds.

Wegovy and Ozempic are the same drugs but with different names and different doses for different conditions. Wegovy is the name of the drug as it is prescribed for weight loss. Ozempic is the name of the drug that is used for diabetes. The generic name for Wegovy and Ozempic is Semaglutide.

Persons taking Semaglutide for weight loss may experience:

Dizziness.
Fatigue.
Gastrointestinal issues, such as diarrhea, constipation, and gassiness.
Headache.
Stomach issues, including nausea, vomiting, pain, or distension (bloat).

The probable causes: Aggressive melanoma and being overweight.

Probable diagnosis: Melanoma stage 3 and overweight.

Treatment plan: Semaglutide to control weight.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.