Can long-term irregular periods affect fertility in women?

Hello,

Welcome to icliniq.com.

I can understand your concern.

The ultrasound shows no significant abnormality detected (attachment removed to protect the patient’s identity). However, despite a normal scan, you have been having irregular periods since menarche (the beginning of menstruation) and infertility.

This suggests a functional or hormonal issue, such as:

I would like to inform you that these are possible causes of irregular periods and infertility:

1. Polycystic ovary syndrome (PCOS), even if not visible on ultrasound, can still be present and is typically assessed through follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels.

2. Thyroid imbalance.

3. High prolactin levels.

4. Low ovarian reserve, especially if periods are too light or absent for long stretches.

I would suggest a few investigations to do, if not already done, to check levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) to evaluate ovulatory function. Prolactin levels should be checked, as elevated levels can disrupt normal menstrual cycles. Thyroid-stimulating hormone (TSH) is important to assess thyroid function, which can also impact fertility. Anti-Müllerian Hormone (AMH) helps determine ovarian reserve. In addition, hormonal profiles such as serum testosterone and dehydroepiandrosterone sulfate (DHEAS) are useful for identifying androgen excess. Imaging investigations, like a pelvic Doppler or transvaginal ultrasound, can assess the uterus and ovaries. Lastly, a partner's semen analysis is essential to evaluate the male factor in infertility.

And about your medications, Fertilix Ova (Fertilix Ova is a fertility supplement containing CoQ10, myo-inositol, folic acid, vitamins D, E, C, NAC, zinc, and selenium) is a dietary supplement to improve ovarian function in women with suspected ovulatory issues. Purayati folate (it contains Quatrefolic (570 µg), iron (27 mg), inositol, and choline hydrogen tartrate), a folic acid supplement, is important for preconception health. You should consider restarting these as advised by your gynecologist.

Your next steps should be to,

1. Consult a fertility specialist.

2. Restart your supplements.

3. Follow a balanced diet and make lifestyle changes.

4. Track ovulation (using kits or follicular scans).

5. Consider Clomiphene Citrate (selective estrogen receptor modulator) or Letrozole (aromatase inhibitor). Induction therapy under medical supervision is recommended if you are not ovulating regularly.

I hope this helps.

Take care.