Metformin is an antidiabetic drug used as the first-line medication for the treatment of type 2 diabetes, especially in overweight patients. It works by restoring your body's response to the naturally produced insulin. It also reduces the blood sugar by decreasing the sugar production in the liver and its absorption in the intestine.

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My sugar levels are high. What to do next?

Query: Hello doctor, I am a 41 year old female. I had GDM 9 years back with twin pregnancy. Post-delivery for few months my blood sugars were normal. Later l was started on tablet Metformin 500 mg SR bd along with diet control. Last year l was started on tablet Atenolol 5 mg od. l feel fatigue even after...  Read Full »

Dr. Divakara. P

Answer: Hi, Welcome to Your blood sugars are quite high and the dose of medication (Metformin 500 mg twice a day) is becoming inadequate for you. You need to be started on stronger medicine. I would recommend you to take tablet Glycomet GP1 (Glimepiride and Metformin combination) in the morni...  Read Full »

How to reduce levels of cortisol?

Query: Hi doctor, I am a 25 year old female. Is there any way to effectively reduce elevated cortisol and aldosterone? But, it is not Cushing's. I just have too high cortisol for the last few years and weight loss problem.  Read Full »

Dr. Divakara. P

Answer: Hi, Welcome to There are medicines for that, but it would be a temporary solution. We need to find the cause of elevated cortisol and aldosterone. In that regard, kindly upload the tests reports. Also, let me know, are you on any birth control pills?  Read Full »

My sugar levels are under control after using Insulin and Metformin. Should I still continue them?

Query: Hi doctor, I am a diabetic male smoker aged 50. I take insulin 12 IU/mL at night and 24 IU/mL in the morning. I also take Metformin 850 mg twice a day. My sugar level has always been above 150 mg/dL but now it is under 90 mg/dL. Should I still take the same dosages? Thank you  Read Full »

Dr. Darshan Kanani

Answer: Hello, Welcome to I read your query and understand your concern. To decide the dose of insulin and OHA (oral hypoglycemic agents), we will need FBS (fasting sugar levels) as well as 2 hrs of PPBS (post-prandial sugar levels). When your HbA1c (hemoglobin A1c) was 15 mmol/mol, you wer...  Read Full »

I have been diagnosed with PCOS and was prescribed Metformin Hydrochloride, but I have not got my periods for the past three months. Please help.

Query: Hi doctor, I have been diagnosed with polycystic ovary syndrome and, also trying to conceive for more than three years ago. I consulted a doctor and he has prescribed me Metformin hydochloride. However, it has been three months since there have been no signs of a period. This Metformin hydrochloride...  Read Full »

Dr. Richa Agarwal

Answer: Hi, Welcome to Thank you for your query, Menstrual irregularities could be due to hormonal imbalance cause by polycystic ovarian syndrome. Polycystic ovarian syndrome is a endocrinal disorder in which hormonal imbalance will be there due to cyst in ovary, facial hair growth and weigh...  Read Full »

My diabetic father is having frequent urination and insomnia. Could this be due to his occasional alcohol consumption?

Query: Hi doctor,My father has had diabetes for the past 15 years. He is frequently urinating in the night and also struggle to get sleep. He exercises in the morning, eats well, and is physically fit, but occasionally drinks alcohol, recently it has become frequent. Is it due to this? Would his blood sug...  Read Full »

Dr. Muhammad Zohaib Siddiq

Answer: Hi, Welcome to Thank you for your query, There are four reasons for frequent urination. Increase in blood sugar levels. Urinary tract infection. Kidney dysfunctions. Medicines which increase urine. Yes, he should check his blood sugar levels before breakfast in fasting state and...  Read Full »

I manage my blood glucose with a healthy lifestyle, but sometimes it gets high. Do I need Metformin to manage my blood glucose levels?

Query: Hello doctor, I was diagnosed with type 2 diabetes and high triglyceridemia three years ago. My current HbA1C is 6.5 mmol/mol and triglyceride is 212 mg/dL without any medicine. I work out daily, walk 5 km, and maintain my diet also. But sometimes my fasting glucose is 125 mg/dL and my PP is about 1...  Read Full »

Dr. Suneetha B S

Answer: Hello, Welcome to I read your query and can understand your concern. Your blood sugar level is not too high right now, and I have not seen your previous reports when you were diagnosed as having diabetes. Assuming your blood sugar levels were higher earlier, first of all, let me cong...  Read Full »

My gynecologist prescribed hormonal medication and Metformin after I got diagnosed with PCOD. Can I take any alternative medicine?

Query: Hello doctor, I am 25 years old. I had complaints of irregular periods, hair loss, acne, and increased hair growth over the chin. I consulted a nearby gynecologist who told me it will most probably be PCOD and therefore prescribed an OCP and asked to take a pelvic scan for confirmation. I took the s...  Read Full »

Dr. Usha Sadanand Rao

Answer: Hello, Welcome to I read your query and can understand your concern. Yes, the medication to regularise periods is the OCP (oral contraceptives) and you can start taking them. In addition, try to lose some weight. Just losing 5 % of your weight sometimes helps in regularising the periods...  Read Full »

How can fatigue be managed in a patient taking Metformin?

Query: Hello doctor,My father's age is 60 years and is a patient of type 2 DM. He is also a patient of hypertension with an abnormal lipid profile. His RBS is now 360 mg/dl. He is suffering from extreme fatigue although BP is controlled by anti-hypertensive drugs. In this condition, how can we manage fatig...  Read Full »

Dr. Prabhakar Laxman Jathar

Answer: Hello, Welcome to Looking at RBG given (360 mg/100 ml), he has totally uncontrolled diabetes. When this happens there is a lot of glucose lost through urine, leading to excess urination, excess thirst and excess hunger. Plus there is unexplained weight loss and severe tiredness. The rem...  Read Full »

I have PCOS and cannot ovulate even after taking tablets Metformin and Letrozole. Please help.

Query: Hello doctor, I have PCOS. Currently, I am on tablet Metformin and Letrozole. Still, I am not ovulating. My LH levels are 13 IU/L, and my FSH is 4.9 IU/L. Please help.  Read Full »

Dr. Manwani Saloni Dilip

Answer: Hello, Welcome to I read your query and can understand your concern. I can understand that you are worked up about not ovulating despite being on multiple ovulation induction medicines. Please answer the following questions. 1. Have you got an ultrasound done? 2. Did the ultrasound sho...  Read Full »

How to monitor diabetes?

Query: Hi doctor, I am a 30 year old male. My height is 168 cm and weight is 65 kg. I was diagnosed as diabetic one year ago with HbA1c 7.8 and fasting sugar 163. Then I took Kombiglyze XR 1000 mg one tablet a day four months. Then the test revealed¬†HbA1c of 6.6 and fasting sugar 108. Then my doctor reduc...  Read Full »

Dr. Hariharan V

Answer: Hi, Welcome to Instead of Kombiglyze (combination of Saxagliptin and Metformin hydrochloride extended release) take tablet Tenepride (Teneligliptin) and also take Metformin (Exermet or Glyciphage) extended release 1000 mg in the afternoon. Get an x-ray of the pain region and ...  Read Full »

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