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Monkeypox is diagnosed clinically with typical signs. The first stage is characterized by fever, headache, muscle aches, swollen lymph nodes, often in the neck and armpits, and tiredness. The second stage is characterized by a rash on any part of the body, and after one or three days, the fever begins. The lesions of the rash or the blisters develop on any part of the body, including genital areas. It can also spread to other parts of the body. The rash often goes through several stages before scarring and resolving.
This virus can be spread to others by an infected person until all the scabs fall off and a fresh layer of skin appears. The virus-infected patient should get isolated and also treated. It is diagnosed by performing,
Polymerase chain reaction (PCR) - The optimal diagnostic samples for monkeypox are from skin lesions, the roof or fluid from vesicles and pustules, and dry crusts. Where a feasible biopsy is an option, lesion samples must be stored in a dry, sterile tube, not a viral transport media, and should be kept cold.
The vaccines available are,
Food and Drug Administration (FDA) licensed vaccines available for preventing monkeypox infection are JYNNEOS (smallpox and monkeypox vaccine, live, non-replicating), also known as Imvamune or Imvanex, and ACAM2000 (smallpox vaccine, live).
According to the CDC (Centres for Disease Control and Prevention), USA (United States of America), there is a limited supply of JYNNEOS in the USA. On the other hand, there is an ample supply of ACAM2000 available. However, the latter vaccine should not be used in people with some health conditions, including a weakened immune system, skin conditions like atopic dermatitis, eczema, or pregnancy. In addition, no data are available yet on the effectiveness of these vaccines in the current outbreak.
People are considered fully vaccinated about two weeks after their second shot of JYNNEOS and four weeks after receiving ACAM2000.
So, I suggest you get PCR of skin samples done. I hope this has helped you.