Common "Multiple Myeloma" queries answered by top doctors | iCliniq

Multiple Myeloma

Multiple myeloma, alias Kahler's disease, is a type of blood cancer that affects the plasma cells. The signs and symptoms of multiple myeloma include bone pain, loss of appetite, frequent infections, weight loss, and weakness in the legs. The exact cause of multiple myeloma is not known.

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Does my blood reports and symptoms of hip and abdominal pain indicate anything serious?

Query: Hi doctor, I have been experiencing symptoms like nausea and vomiting over the past year, and it has been progressively getting more frequent. I have had persistent, sometimes debilitating, pain in my hip area for the last few months. X-ray and scans so far have revealed nothing. I am often very fat...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. Following is my opinion for your reports and asked questions- 1. IgA (immunoglobulin A) and protein values are increased, but electrophoresis is normal. So, some form of inflammation might be responsible for elevat...  Read Full »

How does multiple myeloma lead to bone pain?

Query: Hello doctor, I recently learned that a close friend, aged 48, has multiple myeloma, and I am quite worried about his health and want to know more about this illness. I want to find out more about why bone pain happens and how it impacts general health and quality of life because I have read that it...  Read Full »


Dr. Raveendran S R

Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. Multiple myeloma is indeed a serious condition that requires understanding and support. It causes bone pain and affects the quality of life for the following reasons. It is a cancer of plasma cells, a type of white b...  Read Full »

I have IgM MGUS without symptoms of WM. What is the further treatment?

Query: Hi doctor, I am 46 years old and I was diagnosed with IgM MGUS at low concentration last month. I am worried about the bone marrow results coming next week. My GP referred me to a hematologist. I do not have the symptoms of WM but hematologists suggest a bone marrow biopsy and CT scan excludes lymp...  Read Full »


Dr. Kamal Kant Sahu

Answer: Hi, Welcome to icliniq.com. Based on the reports, you have IgM MGUS (monoclonal gammopathy of undetermined significance). But we need to confirm it by doing a bone marrow biopsy and it should be less than 10 percent clonal lymphoplasmacytic or plasma cells in the bone marrow. About one percent of pe...  Read Full »

I have chest cold with weight loss, nausea, and dry heaves. Is it multiple myeloma?

Query: Hi doctor, My symptoms include a chest cold for approximately one month, 12 pound weight loss, nausea, dry heaves. Excessive bowel movements. Shortness of breath. Muscle aches. Left side rib pain. Fatigue. I had normal labs except mildly elevated alkaline phosphate. My doctor is now running a ALP i...  Read Full »


Dr. Arvind Guru

Answer: Hi, Welcome to icliniq.com. After reviewing your complaints and your blood investigation (attachment removed to protect patient identity), I can draw the following conclusions: It is highly unlikely that you have multiple myeloma, as your globulins (in blood report) are normal. Though it is a rare s...  Read Full »

What is an immunofixation test?

Query: Hello doctor, I am asking this question on behalf of my dad, who is 60 years old, 5 feet 9 inches, and 173 lbs. He was recently diagnosed with stage three chronic kidney disease. He also recently received an abnormal result on a serum immunofixation test, which I know can be an indicator of multiple...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. As your dad has a chronic kidney disease, he is having nephropathy of the kidneys. We should look out for the cause. It could be high blood pressure or uncontrolled diabetes. He may require dialysis in the later stages. In chronic kidney diseases, active conversion of ...  Read Full »

My WBC is low for the past few years. Why is it so?

Query: Hello doctor, For the past few years during my routine physical my WBC has been low. (2700 to 3700) Neutrophils have run a little low also. No other issues, completely healthy. My dad was diagnosed with multiple myeloma a few years ago but doing well. I have read about some family history with this ...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. According to the history provided, your main concern is regarding fear of multiple myeloma. In case of a multiple myeloma like malignancy, there is usually the presence of weakness, fatigue and bone pain. In multiple myeloma, osteolytic bone lesions occur and so bone...  Read Full »

Why do my temples get swollen when I chew hard food?

Query: Hi doctor, I get a swelling on the temple after chewing on hard food, for example, steak or candy. The swelling goes down after I stop eating, but the area feels numb for a long time after that. What can cause this? I have chronic urticaria and MGUS.   Read Full »


Dr. Muhammad Majid Hanif

Answer: Hello, Welcome to icliniq.com. I have carefully reviewed your health query and will answer your concerns. The issues you mentioned are related to mastication (chewing). It is a process where you have to put a lot of energy, and the muscles of mastication are widely used. It seems there is some ne...  Read Full »

Can multiple myeloma be diagnosed only by doing blood tests and X-rays?

Query: Hi doctor, I am a 63 year old male. I have been recently diagnosed with multiple myeloma. My doctor, who is listed as a hematologist or oncologist, said that I must undergo chemotherapy asap. His diagnosis was based solely on bloodwork and a full skeletal x-ray. There was no MRI or PET scan or bone ...  Read Full »


Dr. Sagar Ramesh Makode

Answer: Hi, Welcome to icliniq.com. Blood tests can provide compelling indications of myeloma; however, a marrow biopsy remains essential for confirmation. While a diagnosis can be reasonably presumed, it's imperative to undergo a bone marrow biopsy prior to commencing treatment. If visible on an X-ray, bo...  Read Full »

I have intermittent blood protein levels. Is it worrisome?

Query: Hi doctor,For around seven years, my blood protein levels range from 8 to 8.6. The average of all is 8.29 and nothing showed up in urine. Is this a precursor to something? When I asked doctors, they all said that it was in guidelines and it is intermittent.  Read Full »


Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: Yes, your doctor is right. Variation in protein levels is always present. Only, if the globulin levels are too high, then it is worrisome. If the globulin levels are increasing over time, then you need to be worried. If not, ...  Read Full »

Should I be screened for myeloma if my father had it?

Query: Hello doctor,My father was diagnosed with myeloma. I am 28 years old and wondering if myeloma is hereditary. And if it is then should I be screened? If so at what age?Please help.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to the icliniq.com. The exact cause for myeloma is still not identified with 100 % results. But it is not hereditary as per a few books because it is plasma cell dyscrasia and plasma cell problem is acquired, not genetic. The causes of myeloma are as follows; 1. Radiation ex...  Read Full »

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