How to prevent MS progression in women?

Question

Hello doctor,

I am a 28-year-old female recently diagnosed with MS after an MRI revealed lesions. I have been experiencing numbness in my legs and blurry vision. I am concerned about the possibility of ending up in a wheelchair.

My neurologist has suggested treatment options, including injections or oral medications, but I am uncertain which would be more effective.

Are there any new treatments available that can prevent the progression of the disease?
Does pregnancy exacerbate MS?

Kindly help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query and understood your concern.

Let me explain step by step.

Multiple sclerosis (MS) is a condition in which the immune system attacks the covering of nerves, leading to relapses (episodes of symptoms) and sometimes gradual progression. The good news is that with today’s treatments, many people live full lives and do not end up in a wheelchair.

There are several types of disease-modifying therapies (DMTs). They do not cure MS, but they can reduce relapses and slow down disability.

Here they are:

Injections (such as Interferons and Glatiramer): Older, safer, but less strong.
Pills (such as Fingolimod and Dimethyl Fumarate): More convenient, moderate strength, and some monitoring needed.
Infusions (such as Ocrelizumab and Natalizumab): Very effective for aggressive disease, given every few months.

Your neurologist usually chooses based on your disease activity, MRI (magnetic resonance imaging) findings, lifestyle, and pregnancy plans.

Newer treatments are highly effective. Monoclonal antibody infusions (such as Ocrelizumab, Ofatumumab, Ublituximab) are newer options that strongly reduce relapses and MRI activity. They have changed the outlook of MS in the last few years.

Pregnancy usually reduces MS relapses, especially in the later months. After delivery, there can be a short-term increase in relapse risk. Most women with MS carry pregnancies safely, but medication planning is important because some drugs are not safe during pregnancy.

With early and appropriate treatment, most young women with MS continue walking, working, and living independently for decades. Lifestyle factors such as good sleep, vitamin D, exercise, and not smoking also help.

I hope that this answers your query.

Kindly follow up if you have more doubts.

Thank you.