Q. Can excision biopsy remove the nodal metastasis in nasopharyngeal carcinoma?

Answered by Dr. Saurabh Samdariya and medically reviewed by iCliniq medical review team.


Do you have a question on Nasopharyngeal Carcinoma or Lymph Node Biopsy? We have medical experts to help you right away. Ask a Doctor Now »

Hi doctor,

My son was recently diagnosed with nasopharyngeal carcinoma stage 3. He had undergone 35 sessions of IMRT as well as six sessions of chemotherapy. Three more sessions of chemotherapy have been prescribed and the first one was completed last week. Two more to go in three weeks time. Recently his treating doctor found more lymph nodes in his jugular and submandibular regions. FNAC reported a highly suspicious deposit from a malignant carcinoma and excised biopsy was recommended. Is it safe to perform the biopsy? Will all the lymph nodes be removed during the operation? Patient is underweight and not eating well, will anaesthesia be performed in such cases? Will IMRT be required again and is that even possible to do it again? What are the options?

Related Questions:
How common is it for a surgeon to remove salivary gland instead of a lymph node?
Please explain about non-Hodgkin lymphoma in detail.
Can you clarify the term effaced lymphoid tissue in my pathology report?

Dr. Saurabh Samdariya
Radiation Oncology


Welcome to icliniq.com.

First of all, based on the reports, the patient is hypovolemic (low BP). He needs a good oral diet and maybe if required admission and supportive care in the form of IV fluids. It looks like a recurrent disease in sub-mandibular nodes. It needs to be evaluated whether the nodal levels were included in the radiation therapy field or not (in-field recurrence vs out-field recurrence). In-field recurrences are difficult to treat and second-line chemotherapy or surgery can be planned (depending upon the response at the primary site: nasopharynx). Out of filed recurrence can be treated by radiation dose only if the meaningful dose of radiation has not been delivered in those regions. The biopsy can be performed if FNAC results are doubtful. You have not mentioned the date of completion of radiation therapy. Further course of action will also depend on that.

Ask your health query to a doctor online?
Ask a Doctor Online »
* guaranteed answer within 4 hours.

Ask your health query to a doctor online?
Ask a Doctor Online »
* guaranteed answer within 4 hours.

Ask a Doctor Online

* guaranteed answer within 4 hours

Most Viewed

Are Fraxinud allergy and olive trees allergy same?
Hello doctor, Would you please explain if this means I have allergy from olive trees (trees that produces olives), if I ...Read more »
Is there a chance for a baby inspite of suffering from ED and teratozoospermia?
Hello doctor, We are trying from past two years for a baby. I am facing an ED problem, and I am advised to take Penegra ...Read more »
Tinnitus - Symptoms, Causes, Risk Factors, and Treatment
Tinnitus or ringing in the ears is a common symptom seen due to various reasons. This article talks in detail about tinn ...Read more »

Also Read Answers From