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What are the best treatment approaches for obesity?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 34-year-old woman who has been struggling with obesity since adolescence. My BMI is 39, and I also have irregular menstrual cycles, fatigue, and high cholesterol. Despite multiple attempts with dieting, exercise, and even prescription weight-loss pills, I keep regaining weight.

I have read about bariatric surgery and newer injectable medications, but I am worried about long-term safety and whether they help with hormonal balance and fertility. What treatment approach would be best for me?

Please help.

Thank you.

Answered by Dr. Neha nigam

Hello,

Welcome to icliniq.com.

I understand your concern.

Weight regain from adolescence into adulthood is common, and it also means that weight loss is possible. There are many available treatment options, diet plans, and exercise programs, but the key factors are patience and persistence. I understand that adolescence to adulthood is a long period.

Before prescribing any medication, I would like to review some investigations.

Please let me know:

  • Are your periods or menses reduced in amount?
  • How infrequent are they, and for how many days do you bleed?
  • Do you have acne or facial hair growth?
  • Are you on any medications, such as for thyroid disorders, diabetes, or hypertension?
  • How often do you feel hungry? Do you experience binge-eating episodes?
  • Is there a history of diabetes or lipid disorders on the maternal or paternal side?
  • Do you have children?

I am advising some tests, please get them done and share the reports. For you, if treatment, exercise, and diet help reduce weight, you must stick to that plan long-term. This is primarily a lifestyle-related problem.

For fertility concerns, it is better to adopt a healthy lifestyle with:

  • Daily diet planning.
  • Healthy, home-cooked meals with fixed portions.
  • A regular exercise plan (at least 45 minutes daily).
  • Reduced stress and anxiety.

First, we should focus on reducing BMI (basal metabolic index) with appropriate measures, and then create a personalized plan that you must follow for long-term benefits. Injectable treatments can be considered, but weight gain often returns after stopping them. These are only add-on options.

We must first understand the real cause of weight gain, and only then can an effective treatment plan be made.

  • The probable causes of weight gain are metabolic syndrome and PCOS (polycystic ovarian syndrome).
  • Investigations to be done are lipid profile, HbA1C, fasting blood sugar serum thyroid stimulating hormone (Serum TSH), free thyroxine (Free T4), serum prolactin (Serum PRL), homeostatic model assessment of insulin resistance (HOMA-IR), liver function tests (LFT), renal function tests (RFT), serum total testosterone, and dehydroepiandrosterone sulfate (DHEAS).
  • Follow up if you have any old reports; you can share them with me.
  • Preventive measures include a fixed-calorie diet and exercise for 45 minutes.

I hope this helps.

Please follow up if you have any further concerns.

Thank you.

Answered byDr. Neha Nigam

Medically reviewed byiCliniq medical review team

Published At March 14, 2026
Reviewed AtMarch 18, 2026

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Neha nigam
Dr. Neha nigam

Obstetrics and Gynecology

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