Common "Paget's Disease" queries answered by top doctors | iCliniq

Paget's Disease

Paget's disease is a chronic disease affecting the bones. They disturb the remodeling process of the bone, resulting in the replacement of new bone with weak and brittle bones. This disease is usually symptomless, and in severe cases, it causes bone deformities. There is no cure for Paget's disease, but osteoporosis drugs are taken orally to relieve the symptoms seen in Paget's disease.

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Can I inherit Paget's disease from my grandmother?

Query: Hi doctor, Is Paget's disease inherited? My Grandmother had it. I am going to do PRP hair treatment. Could this be a trigger for Paget's?  Read Full »


Dr. Anuj Nigam

Answer: Hi, Welcome to icliniq.com. Paget's disease has been associated with both genetic (family) and environmental factors (climate, locality, ethnicity, race, etc.). A parent has a chance of transferring the disease to the child is seven to ten times more. There has not been any evidence of trigger fac...  Read Full »

I have Li-Fraumeni Syndrome. Should I be concerned about this nipple pain?

Query: Hello doctor, I have Li Fraumeni Syndrome which greatly increases my chances of cancer. I have regular various annual screenings. I had a breast MRI three months back and the report (which I do not have) stated that the contrast seemed to 'pool' in one place. The doctor said he was not overly conce...  Read Full »


Dr. Sagar Ramesh Makode

Answer: Hello, Welcome to icliniq.com. Paget's disease mostly involves nipple and later spread to areola, but it can also involve areola only. It is possible that areola is involved and the nipple is swollen. Many cases of Paget's disease do have lump below the nipple or some cancerous lesion. Is this lesio...  Read Full »

My grandmother has been suffering from Paget's disease of the bone. Can I acquire the same disorder?

Query: Hi doctor, I have two questions regarding Paget's bone disorder. 1. My grandmother has the condition. Do I have an increased risk of getting it? 2. I am going to do a PRP treatment for hair loss. Could this procedure trigger Paget's? Thinking of the needle may be hitting the bone in the skull or a ...  Read Full »


Dr. Zulfiqar Ahmed

Answer: Hi, Welcome to icliniq.com. I understand your concern. Paget's disease of the bone is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated...  Read Full »

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