Dr. Anuj Nigam
Orthopedician and Traumatology
The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.
Answered by
Medically reviewed by
Patient's Query
Hi doctor,
Is Paget's disease inherited? My Grandmother had it. I am going to do PRP hair treatment. Could this be a trigger for Paget's?
Hi,
Welcome to icliniq.com.
Paget's disease has been associated with both genetic (family) and environmental factors (climate, locality, ethnicity, race, etc.). A parent has a chance of transferring the disease to the child is seven to ten times more. There has not been any evidence of trigger factors as far as I know for disease development. It is an Autosomal Dominant type of inheritance. PRP (Platelet-rich plasma) is a relatively safe procedure for hair treatments because it locally acts on the hair bulbs and hair roots to induce growth and does not usually have a broad Systemic (full body) effect. PRP (Platelet-rich plasma ) is made from your own blood, so no immunosuppression is required. However, as you have a family history of Paget's, it's always better to keep a precaution and get some blood tests before and after the PRP (Platelet-rich plasma) procedure, especially for Routine Blood investigation with Serum calcium, Vitamin D3, Alkaline Phosphatase, that is, deranged in Paget's disease. If at the time found to be different than normal, the treatment for the same can be initiated. It is recommended for all people above 40 years old to take supplements of calcium and Vitamin D3 to prevent Osteoporosis and help maintain bone strength during advancing age. You can go for PRP (Platelet-rich plasma ) treatment under a qualified doctor or PRP (Platelet-rich plasma) specialist without any doubt.
Thank you
Patient's Query
Hi doctor,
Thanks for your answer. Is the risk still seven to ten if my grandmother had Pagets? So you do not think PRP will trigger Pagets?
Hi,
Welcome back to icliniq.com.
The risk is much lesser if non of your parents developed the disease. As I told you, PRP (Platelet-rich plasma ) does not require any heavy immune suppression or serious immune response, as PRP (Platelet-rich plasma) is made from your own blood the chances are minimum. However, the human body is unpredictable hence there is nothing 100% guaranteed. You can go for the treatment if your doctor performing the procedure is confident and experienced in the therapy and you have faith in him.
Thank you.
Was this conversation helpful?
Same symptoms don't mean you have the same problem. Consult a doctor now!
Orthopedician and Traumatology
Related Questions
Bone Density Scan - Indications, Procedure, Results, Benefits, and Risks
Osteogenesis Imperfecta - Types, Symptoms, Manifestations, Diagnosis and Treatment
Why do I hear ringing noise and low-pitched humming alternatively?
A piece of bone has protruded through my gums and is causing tongue ulcers. What to do?
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.
This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy
