Patient's Query
Hello Doctor,
I am 56 years old and was diagnosed with Parkinson's disease 18 months ago. Lately, I feel like the medications are not working as well as they used to. The tremor in my right hand has gotten worse, and now it affects my left hand too. My handwriting has become so small that I cannot even read it, and I am starting to have trouble using the keyboard at work.
My muscles feel stiff, and it is very hard to do simple things like buttoning my clothes or opening jars. I walk more slowly now, and my balance is getting worse. I have fallen twice in the past month. The medicine Carbidopa-Levodopa helps for a few hours, but then it wears off, and I feel stuck or "frozen" during those off periods.
My neurologist increased the dose, but now I have dyskinesia, which causes involuntary movements that are almost as upsetting as the tremors. I am only 56, but I feel like I am aging very quickly. My teenage daughter is scared and asks if I will end up like her grandfather, who also had Parkinson's disease.
I work as an accountant, but I am worried that my symptoms might cause me to make mistakes. The fatigue is overwhelming. I sleep for 12 hours, but still feel tired.
Should I think about having deep brain stimulation surgery? Are there any newer medications that might help me more? I need to understand what the future might look like with this disease so I can make plans for my family.
Kindly help.
Hello,
Welcome to icliniq.com.
I understand your concern.
The symptoms you are describing, worsening tremor, stiffness, changes in movement control, and involuntary movements, are common after a few years of taking Carbidopa-Levodopa, especially in people who develop Parkinson’s disease at a younger age. The good news is that there are still many options available to help you.
Other medications can be added to help reduce the “off” times and allow you to take lower doses of Levodopa. Catechol-O-methyltransferase inhibitors like Entacapone can help Levodopa last longer in your body. Monoamine oxidase type B inhibitors like Rasagiline or Safinamide can help reduce the breakdown of dopamine and may give some extra benefits on their own. Dopamine agonists such as Pramipexole or Ropinirole act like dopamine in the brain and can help with symptoms. However, they may cause side effects like mood changes or impulse control problems, especially in younger people. These medication changes are best handled by a movement disorder specialist, a neurologist who has special training in Parkinson’s disease. If you have not seen one yet, it is a good idea to do so.
Because you are having strong ups and downs with your medication and also dealing with involuntary movements, you may be a good candidate for deep brain stimulation surgery. This procedure does not cure Parkinson’s disease, but it can help control symptoms more smoothly, reduce off periods, and lessen the amount of medication you need. Many people feel they have a better quality of life after this surgery. A movement disorder specialist can decide if you are a good fit for this treatment by doing a full check-up and brain scan.
Supportive therapies are also very helpful. A physical therapist trained in Parkinson’s disease can help you with walking, balance, and strength, which may lower your risk of falling. An occupational therapist can teach you easier ways to manage daily tasks like buttoning clothes, using the keyboard, or opening jars. They can also help you feel more confident at work.
Feeling very tired is a common and serious part of Parkinson’s disease. Even if you sleep a lot, you can still feel exhausted. This could be caused by sleep problems, depression, or the disease itself. It is a good idea to check for things like sleep apnea, restless legs syndrome, or depression. These problems are common in people with Parkinson’s disease. Sometimes changing your medications or adding something like Modafinil, a wakefulness-promoting medicine, may help with fatigue.
Your daughter’s fears are understandable. This is a chance to talk openly with her and show her that, with good care and planning, Parkinson’s disease can be managed. Yes, it is a progressive condition, but many people live meaningful, active lives for many years after diagnosis. You can start planning now for the future by looking into legal documents, work accommodations, and family support. This can help you feel more prepared and give your family peace of mind.
You are handling a very tough situation with strength and care. You are thinking not only about your health, but also about your daughter and your responsibilities. You deserve every chance to feel better and stay independent. Please consider talking to a movement disorder specialist soon. Ask about deep brain stimulation and other advanced treatments that may help you live the life you want.
I hope you are satisfied with my answer. For further queries, you can consult me at iCliniq.
Thank you.
Was this conversation helpful?
Answered byDr. Aissa Youcef Mouffoki
Medically reviewed byiCliniq medical review team
Same symptoms don't mean you have the same problem. Consult a doctor now!
Related Questions
Parkinson's disease patient fell down and unable to walk, why?
How to manage Parkinson’s with persistent vomiting?
Oral Tardive Dyskinesia
Atypical Parkinson’s Disease - Causes, Symptoms, and Treatment
What is the treatment for progressive Parkinson's disease?
ADCY5-Related Dyskinesia - An Overview
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.