Patient's Query
Hello doctor,
My father, aged 68, has been diagnosed with Parkinson’s disease. He has hand tremors and mild slowness in walking. The MRI brain was normal, and he has been started on the Levodopa-Carbidopa combination. My concerns are:
How long does it usually take before symptoms improve noticeably?
Are there any foods or supplements that can interfere with the medicine’s absorption?
We noticed occasional dizziness when he stands up suddenly. Is that a side effect or low blood pressure from the drug?
Also, do physiotherapy or hand exercises actually help maintain muscle strength and balance in Parkinson’s, or are they mainly supportive without slowing progression?
Kindly suggest.
Thank you.
Hello,
Welcome to icliniq.com.
I understand your concern.
Thank you for writing in. It is clear how much you care about your father. On the question of when you will see improvement, Levodopa usually starts working within 30 to 60 minutes of taking a dose. Noticeable improvement in slowness and stiffness often comes relatively quickly, which can feel quite reassuring.
Tremor can sometimes be a little less responsive to the medication, though, so do not be discouraged if that particular symptom takes more time or improves only partially. Regarding food and supplements, this is something worth being careful about.
High-protein meals can interfere with Levodopa absorption, so it helps to take the medication 30 to 60 minutes before meals, where possible. Iron supplements should also be avoided close to dose time, as they can affect how well the medication is absorbed.
Small adjustments like these can actually make a meaningful difference to how consistently the medication works throughout the day. The dizziness your father experiences when standing up suddenly is a common side effect and is often caused by a drop in blood pressure triggered by the medication.
The simple fix is to encourage him to rise slowly from a sitting or lying position, giving his body a moment to adjust. It is worth mentioning to his doctor at the next visit, just so they are aware and can monitor it. As for physiotherapy and hand exercises, yes, they are genuinely very important and not just supportive in a minor way.
Physiotherapy helps maintain strength, balance, and mobility in a real and practical sense. While it does not slow the progression of the disease itself, it significantly improves quality of life and day-to-day function, which matters enormously for someone living with Parkinson's.
Keeping him active and engaged with a good physio routine is one of the best things you can do alongside the medication. You are asking all the right questions, and your father is lucky to have someone looking out for him this carefully. Do not hesitate to reach out if anything else comes up.
I hope this helps.
Thank you.
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Answered byDr. Kanishka Sharma
Medically reviewed byiCliniq medical review team
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