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Does a higher dose of Quetiapine than the required dose affect the brain?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have always taken low doses of medication, such as Quetiapine extended-release (50 to 100 mg). My medicine was suddenly increased (300 mg) - not just slightly, to the lowest effective amount, but three times more. Can my brain become accustomed to taking these medications in such huge doses (which may be too high for me - the effective amount may be lower)?

Kindly help

Answered by Dr. Vipul Chelabhai Prajapati

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

First and foremost, if you are seeing improvements with a low dosage, there is no need to increase it. However, if you wish to raise the dosage because you did not achieve the intended result, there is no need to worry. As a result, tolerance will not grow. Once you are stabilized on a certain dosage, your treating doctor will progressively reduce the dosage of the medicine.

So do not worry, your brain will not adjust and you won't need a greater dose every time.

I hope this helps.

Thank you and take care.

Regards.

Medically reviewed by iCliniq medical review team
Published At February 18, 2025
Reviewed At February 18, 2025

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Vipul Chelabhai Prajapati is a Psychiatrist skilled in diagnosing and managing a wide range of mental health conditions. His expertise includes mood disorders (depression, bipolar disorder), anxiety disorders, psychotic disorders (such as schizophrenia), substance use disorders, child and adolescent psychiatry, geriatric psychiatry, and psychotherapy. He is also experienced in stress management, counseling, and rehabilitation support.

This doctor is not available for online consultations on the platform anymore.

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