Can a RH negative mother successfully deliver second baby?

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It is good to know about family rhesus sensitization for better care. If both parents have a negative blood group, then there would be no problem, but if the mother is negative and the father positive with rhesus positive child, and the baby's blood enters in mother during injury, birth, or bleeding, sensitization occurs, and the mother's immune system can develop antibodies (infection-fighting protein) against rhesus antigen. This is known as rhesus sensitization. As I told you, this sensitization occurs at birth, an injury, or a bleed. When the mother becomes pregnant with a second baby with a positive blood group, she already has sensitization, so her blood's antibodies can attack the baby's blood cells and thus cause hemolytic anemia or jaundice in the newborn. Injection of anti-D antigens, if given to the mother, can reduce the risk of sensitization by preventing the production of antibodies and clearing the antigen against blood cells. It is recommended for Rh-negative women to have antigen if it gets sensitized, like in case of bleed or trauma. Still, at 28 and 32 weeks, an anti-D injection will be given for all negative asymptomatic women. I would suggest getting this test to check your wife's antibody level. Get your baby reviewed by a neonatologist at birth. I hope I have cleared all your doubts. Hope I have cleared all your doubts.

Thank you.