Schistocytes are the part of a fragmented red blood cell, which are irregular in shape, jagged with two sharp ends. It is most commonly seen in people with microangiopathic hemolytic anemia and is a result of damaged endothelium. Schistocyte count less than 0.5% is normal; however, a value less than 0.2% is usual. In thrombotic thrombocytopenic purpura, schistocyte count range between 3 to 10%, and values between 0.5 to 1% indicate disseminated intravascular coagulation.
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Query: Hello doctor, Please interpret the liver biopsy report shown below. Kindly explain the what stage of fibrosis and confirm whether cirrhosis is present or not. Pathological diagnosis: A. Liver parenchyma biopsy: Steatohepatitis with perisinusoidal and periportal fibrosis. Note: The biopsy ... Read Full »
Answer: Hello, Welcome to icliniq.com. The most common cause of periportal and perisinusoidal fibrosis with chronic inflammatory cell infiltration is due to steatohepatitis in both alcoholic and non-alcoholic. However, chances are very high in alcoholics. Periportal fibrosis can occur due to Schistosoma ... Read Full »
Query: Hi doctor, My friend recently got a blood test done and they told her that she had a large number of schistocytes. However, she was not found to be anemic and has no other history of serious health issues. She is 30 and thin built. She has been anemic on blood tests occasionally in the past. I do... Read Full »
Answer: Hi, Welcome to icliniq.com. I have gone through your query and can understand your concern. Schistocytes are nothing but fragmented or broken red blood cells, which are formed due to trauma to the cells. There are many causes of schistocytes in blood, One of the causes is microangiopathic hemol... Read Full »
Query: Hello doctor, I am a 53 year old woman diagnosed with polycythemia vera (PV) three years ago. I am being treated with phlebotomy. I have fatigue at times, as well as some thinking impairment at times. Over time I have developed various anomalies in my blood test results, which my doctor explained as... Read Full »
Answer: Hi, Welcome to icliniq.com. Based on your query regarding polycythemia, my opinion is as follows: Due to nutritional deficiencies, secondary to excessive RBC (red blood cell) production and also mild dyserythropoiesis (defective development of red blood cells), you can find microcytic hypochromic... Read Full »
Query: Hi doctor, My wife's iron and ferritin were low, so the doctor ordered CBC. CBC showed low WBC, high monocytes, and high RBC, which is what made us scared. She has schistocytes and elliptocytes among other RBC morphologies. We read about it and are very worried, and she had a C-section three years... Read Full »
Answer: Hello, Welcome to icliniq.com. I have gone through your wife's reports (attachment removed to protect patient identity). The report shows schistocytes, which are fragmented RBC (red blood cell), commonly seen in hemolytic anemia. So, to rule out hemolysis, serum LDH (lactate dehydrogenase), ret... Read Full »
Query: Hello doctor, My husband's hemoglobin is 3.7 g/dL, but the hemoglobin level was 5 g/dL when we checked it two days back. His RBC and WBC are also going down. What can be the reason? Read Full »
Answer: Hi, Welcome to icliniq.com. Your husband's hemoglobin and WBC count are going down very fast, it is not normal. For such low hemoglobin levels, blood transfusion is needed immediately. A peripheral smear examination should be done, to look for schistocytes like fragmented RBC and normoblast count... Read Full »