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Do schistocytes in a blood smear report suggest thalassemia minor?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am attaching my latest blood smear report, which shows I have schistocytes. I did not have them initially, so I repeated my blood tests to confirm, and they were not there the next time. However, I always had elliptocytes in my blood.

I have been taking folic acid supplements as suggested by my doctor. Also, I have had blood smear, hemogram, LDH, erythrocyte osmotic fragility, vitamin D, vitamin B12, and ferritin levels checked.

Do I have thalassemia or microangiopathic hemolytic anemia?

Kindly advise.

Thank you.

Answered by Dr. Mubashir Razzaq Khan

Education:

MBBS

Professional Bio:

Dr.Mubashir Razzaq Khan is working as a clinical Hematologist for the past 19 years. After completing his MBBS at Punjab Medical College Faisalabad, he did MPhil, Ph.D., and MCPS at Postgraduate Medical Institute Lahore. He treated thousands of patients with Anemia, Thrombocytopenia, Leukemias, Thalassemia, Hemophilia, Thrombosis, Aplastic anemia, Fanconi anemia, and Hereditary disorders. Currently, he is working at Chughtai Medical Center, Faisalabad, Punjab, Pakistan.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

I have reviewed your reports (attachment removed to protect the patient's identity). Your reports point towards thalassemia minor (or carrier) or recovery from iron deficiency. Additionally, certain allergic conditions can increase your eosinophils and basophils. You must continue taking vitamin B12, folic acid, pyridoxine, and vitamin D supplements.

Additionally, consider using antihistamines and leukotriene inhibitors to manage allergies. You can ask your doctor to prescribe deworming medication for you. I suggest you repeat the hemoglobin electrophoresis test and gene mutation testing for thalassemia.

I hope this helps.

Thank you.

Patient's Query

Hello doctor,

Thank you for the reply.

I am sharing the reports of my recent electrophoresis. One of the blood smears shows schistocytes. Should I be worried about it?

Kindly advise.

Thank you.

Answered by Dr. Mubashir Razzaq Khan

Education:

MBBS

Professional Bio:

Dr.Mubashir Razzaq Khan is working as a clinical Hematologist for the past 19 years. After completing his MBBS at Punjab Medical College Faisalabad, he did MPhil, Ph.D., and MCPS at Postgraduate Medical Institute Lahore. He treated thousands of patients with Anemia, Thrombocytopenia, Leukemias, Thalassemia, Hemophilia, Thrombosis, Aplastic anemia, Fanconi anemia, and Hereditary disorders. Currently, he is working at Chughtai Medical Center, Faisalabad, Punjab, Pakistan.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

I understand your concern.

Your hemoglobin electrophoresis test is normal. However, as you might have thalassemia minor, I suggest you continue using the supplements and undergo gene mutation testing.

I hope this helps.

Thank you.

Medically reviewed by iCliniq medical review team
Published At September 10, 2022
Reviewed At June 8, 2026

Education:

MBBS

Professional Bio:

Dr.Mubashir Razzaq Khan is working as a clinical Hematologist for the past 19 years. After completing his MBBS at Punjab Medical College Faisalabad, he did MPhil, Ph.D., and MCPS at Postgraduate Medical Institute Lahore. He treated thousands of patients with Anemia, Thrombocytopenia, Leukemias, Thalassemia, Hemophilia, Thrombosis, Aplastic anemia, Fanconi anemia, and Hereditary disorders. Currently, he is working at Chughtai Medical Center, Faisalabad, Punjab, Pakistan.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr.Mubashir Razzaq Khan is working as a clinical Hematologist for the past 19 years. After completing his MBBS at Punjab Medical College Faisalabad, he did MPhil, Ph.D., and MCPS at Postgraduate Medical Institute Lahore. He treated thousands of patients with Anemia, Thrombocytopenia, Leukemias, Thalassemia, Hemophilia, Thrombosis, Aplastic anemia, Fanconi anemia, and Hereditary disorders. Currently, he is working at Chughtai Medical Center, Faisalabad, Punjab, Pakistan.

This doctor is not available for online consultations on the platform anymore.

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