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Is it safe to take compounded Semaglutide?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I need answers about compounded Semaglutide. I am 38 years old, 5 feet 7 inches tall, and weigh 290 pounds, with worsening PCOS and insulin resistance. I have tried every diet imaginable with minimal success, and now my fertility specialist says I need to lose 50 pounds before we can try in vitro fertilization. Time is not on my side. A medical spa near me offers compounded Semaglutide for a little cheaper and promises rapid results. They claim it is identical to the FDA-approved version, but it is cheaper. However, I am worried after reading about compounding pharmacies having contamination issues. My endocrinologist seemed hesitant but would not give me a firm no. What are the specific dangers of compounded Semaglutide? Are the effectiveness claims legitimate? Could using this delay my ability to get pregnant? I am desperate but do not want to make a dangerous decision.

Kindly help.

Thank you.

Answered by Dr. Manogna A

Education:

MD

Professional Bio:

Dr. Manogna is a skilled Ophthalmologist passionate about delivering comprehensive eye care and patient education. She is experienced in OPD management, effective communication, and patient-centered care. Dr. Manogna is adept at diagnosing and treating a wide range of eye conditions and provides expert support in surgical procedures, ensuring optimal outcomes and improved vision health for her patients.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and understood it.

The Food and Drug Administration (FDA) does not approve compounded drugs, as it cannot verify their safety or effectiveness. Compounded Semaglutide may increase the risk of low blood sugar (hypoglycemia) and may cause side effects such as abdominal pain, heartburn, and nausea. Serious side effects to watch out for include a rapid heartbeat, shaking, and sweating.

I suggest you take only FDA-approved medications to be safer, after consulting with your treating physician.

I hope this has helped you.

Kindly follow up if you have more doubts.

Thank you.

Answered by Dr. Manogna A
Medically reviewed by iCliniq medical review team
Published At April 20, 2025
Reviewed At April 24, 2025

Education:

MD

Professional Bio:

Dr. Manogna is a skilled Ophthalmologist passionate about delivering comprehensive eye care and patient education. She is experienced in OPD management, effective communication, and patient-centered care. Dr. Manogna is adept at diagnosing and treating a wide range of eye conditions and provides expert support in surgical procedures, ensuring optimal outcomes and improved vision health for her patients.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Manogna is a skilled Ophthalmologist passionate about delivering comprehensive eye care and patient education. She is experienced in OPD management, effective communication, and patient-centered care. Dr. Manogna is adept at diagnosing and treating a wide range of eye conditions and provides expert support in surgical procedures, ensuring optimal outcomes and improved vision health for her patients.

This doctor is not available for online consultations on the platform anymore.

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