Common "Sickle Cell Trait" queries answered by top doctors | iCliniq

Sickle Cell Trait

When a person acquires a normal gene and a sickle cell gene, the person is said to have a sickle cell trait (SCT). The difference between sickle cell trait and sickle cell disease (SCD) is that people with sickle cell trait do not exhibit any symptoms of sickle cell disease, and they pass their trait to their children. In sickle cell disease, the disk-shaped red blood cells become sickle-shaped due to defective hemoglobin. It is an inherited blood disorder. So children of SCD parents may develop SCD or SCT or be free from both. In some instances, people with SCT may experience heat stroke and muscular problems during dehydration and intense physical activity.

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Can sickle cell anemia affect erections?

Query: Hi doctor, About two years ago, I injured my penis using a penis vacuum device. I was using it only for my second time, and it seemed like I overdid it. Also, something to note is that I have sickle cell trait. For the two weeks after the injury, I could not get erections, but then after that, I wa...  Read Full »

Dr. Ankush Jairath

Answer: Hi, Welcome to You have two issues. First is sickle cell, while small arteries like the penile artery can get blocked due to the disease process itself (as in your case). Secondly, as you told during the use of a vacuum device, trauma can greatly potentiate blockage in the already compr...  Read Full »

Is it too risky for me to marry someone with sickle cell trait if I have beta thalassemia trait?

Query: Hi doctor, I have beta thalassemia plus trait (AT+) and want to marry a man with sickle trait (AS). Please see the attached file of my beta thalassemia DNA genetics. Please give me the possibilities of our baby. I know there is a 25 % chance that the baby might have sickle beta plus thalassemia (ST+...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I have seen the reports (attachment removed to protect patient identity). Thalassemia and sickle cell anemia are autosomal recessive disorders. In your case, the child can be thalassemia sickle cell carrier (heterozygous). The presentation will be mild to mode...  Read Full »

Is it rare to see sickle cell anemia and beta thalassemia together?

Query: Hi doctor, My friend is 26 years old. He has sickle cell anemia and thalassemia together. His recent spleen health was good and the proportion of blood and iron was moderate. He does not need to increase the blood. Is it rare to see these two together? What is the average life expectancy of these p...  Read Full »

Dr. Veerendra Channabasappa Patil

Answer: Hello, Welcome to As per your description, your friend seems to be having sickle beta-thalassemia. It is common to see both these diseases together in communities where both diseases are prevailing. Actually, the severity of sickle cell disease comes down by the elevation of the Hb...  Read Full »

Kindly guide me based on the blood electrophoresis report.

Query: Hello doctor, My younger brother's blood electrophoresis report is HbA 61.5, HbS 34.5, and HbF 3.6. So kindly tell me the condition of the patient and precautions to be taken.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to Your attached report (attachment removed to protect patient identity) is suggestive of sickle cell plus beta thalassemia combination case. It can be sickle cell trait as well. For further confirmation, a molecular study can be done. As it is a homozygous condition, t...  Read Full »

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