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How long will it take to completely recover after stem cell therapy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I had a bone marrow transplant using my own stem cells for multiple myeloma a year ago. While my bloodwork looks fine, I feel constantly fatigued, and my immunity seems weaker than before. Is this lingering fatigue normal after stem cell transplantation, and how long does it take for the immune system to fully recover? Are there any long-term risks or complications I should be aware of? Also, what precautions should I take to avoid infections?

Kindly suggest.

Answered by Dr. Sally Attalah

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

It is often described as feeling tired or exhausted after doing little or no activity. Fatigue can occur gradually or suddenly, and it can also occur at any time after a bone marrow transplant (BMT). Energy levels generally improve within a few months, but fatigue can sometimes persist for more than a year after a BMT (two years or more).

The body after BMT is vulnerable to infection as the white blood cells that fight against infection will be in a low count. Bacterial infections are the most common. Viral, fungal, and other infections can also occur. Some infections can develop later on, weeks to months after the transplant.

I hope this helps.

Thank you and take care.

Regards.

The Probable causes

The probable causes include multiple myeloma and BMT (bone marrow transplant).

Preventive measures

You should avoid infection-causing agents for the first year after transplant. Your transplant center may recommend that you avoid crowds, people who have, or have been exposed to infection, people who were recently vaccinated for chicken pox, gardening or digging in the dirt, smoking or being around people who smoke cigarettes, cigars, a pipe, e-cigarettes, or marijuana, walking, wading, swimming, or playing in ponds or lakes, construction sites, and remodeling projects, and well water that has not been treated.

Answered byDr. Sally Attalah

Medically reviewed byiCliniq medical review team

Published At May 6, 2025
Reviewed AtMay 13, 2025

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Sally Attalah
Dr. Sally Attalah

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