Common "Stem Cell Transplant" queries answered by top doctors | iCliniq

Stem Cell Transplant

A bone marrow transplant is a medical treatment that supersedes the bone marrow with healthy cells to treat certain types of cancer. It is of two types: allogenic and autologous transplant. It is used for the treatment of leukemia, lymphoma, and multiple myeloma. Once the stem cells are invested into the patient’s bloodstream, they traverse to the bone marrow and commence the procedure of forming new, healthy blood cells comprising white blood cells, red blood cells and platelets. This process is called “engraftment.”

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All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

I have a relapsed HL tumor despite treatment. Why?

Query: Hello doctor, I am a 52-year-old male, and I was diagnosed with Hodgkin's lymphoma a year back. To date, I have undergone ten cycles of ABVD (Adriamycin, Bleomycin, Vinblastine, and Dacarbazine), but they did not fully remove the tumor. The tumor relapsed again. The doctor advised to do the autolog...  Read Full »


Dr. Arshad Hussain Shah

Answer: Hello, Welcome to icliniq.com. I have read the query, and I can understand your concern. The choice of treatment prescribed for individual patients with relapse depends on several factors, including the histopathological details, IHC (immunohistochemistry), molecular profile, the timing of the re...  Read Full »

Will allogeneic transplantation help multiple myeloma?

Query: Hi doctor, Recently, my mother is diagnosed with multiple myeloma. She had a fast progression. Within a year, the plasmacytoma progressed to MGUS which resulted in multiple myeloma with severe bone involvement. She got a heart attack at the onset of multiple myeloma. I know that deletion of 17p and ...  Read Full »


Dr. Singh Smrita

Answer: Hi, Welcome to icliniq.com. The advantage of allogeneic stem cell transplant is that the donor stem cells make their immune cells. They help to destroy the cancer cells that remain after high-dose treatment. It is called a graft-versus-cancer effect. Autologous stem cell transplant does not offe...  Read Full »

Is autologous stem cell transmission a good option for Hodgkin's lymphoma?

Query: Hi doctor,I was diagnosed with classical Hodgkin's lymphoma. I had eight cycles of ABVD, which did not remove the tumor and the tumor started growing back after four cycles. Then, I went for salvage therapy and that also did not give a good response. Now, the doctor advised to do the autologous stem...  Read Full »


Dr. Erioli Braholli

Answer: Hi, Welcome to icliniq.com. First line therapy of Hodgkin's lymphoma is chemotherapy. ABVD is the most common scheme (Adriamycin, Bleomycin, Vinblastine and Dacarbazine). Second line chemotherapy and radiation may be used if the first therapy fails. As you said in your query that has not had the...  Read Full »

What is the best treatment for Burkitt's lymphoma?

Query: Hi doctor, My 60 year old uncle is diagnosed with Burkitt's lymphoma. His report says MYC-IGH fusion signal was detected in 45 % of the cells. The sample is positive for t(8;14). Could you please suggest whether it is curable and if it is curable then what is the best treatment?  Read Full »


Dr. Janrao Smit Uttam

Answer: Hello, Welcome to icliniq.com. He needs to be admitted urgently to a tertiary care hospital where specialists such as hematologist, oncologist, etc. will be available. An early initiation of chemotherapy with R-CHOP (Rituximab, Cyclophosphamide, Hydroxy daunomycin, Oncovin, Prednisolone) regimen or ...  Read Full »

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