Welcome back to icliniq.com.
I have gone through the reports (attachment removed to protect patient identity). I find that you have been treated for this before five years and an MRI was done. You have again done the MRI after two years. In this MRI, there is an evidence of low lying conus. Let me explain to you what this means. Normally, vertebral column (the bone) grows much faster than spinal cord (the nerve). So, as an individual grows, there is a relative shortening of the spinal cord in reference to the vertebral column. Hence the spinal cord is situated along the upper aspect of the vertebral column and it is not stretched. But, in a few individuals, due to various reasons, the spinal cord is tethered and gets stretched. This stretching interferes with the blood supply. Hence, the patient gets weakness, stiffness, sensation loss, bowel and bladder problems. All the symptoms you have are because of this stretching of the cord. The nerve biopsy you had done was inconclusive, because the problem is actually at the spinal cord level. There are two reasons why it was not visualized in the MRI done earlier, but is seen in the MRI done later as it was in the early stages and became worse after two years and the latest and more power MRI machine found this anomaly. As a treatment, we need to surgically detach the attachments, so that the cord is not stretched. More than 30 people have undergone this surgery in the past two years and the results have been dramatic improvements in their problems and almost all of them are leading a normal life. The probable cause is tethered cord. The treatment plan is to do surgery to release tethering.