Is Tezspire better than Dupixent or Xolair for asthma?

Question

Hello doctor,

I have severe asthma and take my inhalers every day, but I still experience bad flare-ups. My doctor mentioned Tezspire (biological therapy), but I do not fully understand how it works. How is it different from biologics like Dupixent (monoclonal antibody against IL-4(Interleukin-4) receptor alpha) or Xolair (monoclonal antibody against IgE)? Does Tezspire replace inhalers, or do I still need to use them? Also, how often do I have to receive the injection — every week or once a month? Are there any serious side effects I should be concerned about? Most importantly, how much does Tezspire cost with insurance, and is there financial assistance available if insurance does not cover it?

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

I have read your query and can understand your concern.

Tezspire (Tezepelumab) is a newer biologic used for eosinophilic asthma.

I suggest the following test:

Immunoglobulin E (IgE) level.
Eosinophil count tested.

If these levels are high, then Tezspire (Tezepelumab) will be effective.

You need to continue your regular inhalers along with a once-a-month Tezspire (Tezepelumab) injection.

Currently, Tezspire (Tezepelumab) is not covered under most insurance plans.

I hope this helps.

Thank you.