Patient's Query
Hello doctor,
After having severe symptoms, I tested positive for Ureaplasma urealyticum and was given Doxycycline for seven days. I have finished the course, but am still having symptoms.
I believe I need a longer or different course of antibiotics to cure.
I have had severe pelvic pain, discharge, urethral pain and burning, urine frequency, and urgency. I have done a PCR vaginal swab and tested positive for Ureaplasma. Right now, I am taking Amitriptyline 30 mg.
Please help me.
Thank you.
Hello,
Welcome to icliniq.com.
I understand your concern.
Based on the symptoms you described, your condition could be an infection of the uterus and fallopian tubes known as pelvic inflammatory disease (PID), which is typically a sexually transmitted infection.
There are no specific laboratory studies that definitively confirm the diagnosis, so when these symptoms, such as pelvic pain that worsens during sexual intercourse, appear, treatment is recommended empirically to prevent potential complications.
Ureaplasma can be part of the normal vaginal flora and does not usually cause this type of infection on its own; another bacterium is likely involved, which would explain why improvement did not occur with Doxycycline alone.
To treat PID effectively, the following medications are recommended:
A single dose of Azithromycin 500 mg (two 250 mg tablets taken together).
One-time intramuscular injection of Ceftriaxone 500 mg (or one gram in some updated guidelines for better coverage, depending on weight and local protocols).
If the injection cannot be administered, it may be replaced with a single oral dose of Ciprofloxacin 500 mg, though this is considered less effective than the injection.
Additionally, if symptoms have persisted for some time and there is foul-smelling discharge, Metronidazole 500 mg taken every 12 hours for seven days should be added to provide coverage against anaerobic bacteria.
These treatments should lead to complete resolution. This condition is not typically grave or an emergency, but prompt treatment is advised to avoid long-term issues, particularly difficulties in achieving pregnancy later on.
If there is no improvement after this regimen, less urgent conditions such as endometriosis or uterine fibroids can then be considered and ruled out with a transvaginal ultrasound when feasible.
As a first step, however, PID treatment should be initiated, and it is recommended to discuss this with a gynecologist. In the interim, to relieve pain, Ibuprofen 400 mg every six hours can be taken, along with rest as much as possible.
Take all medications after consulting the specialist doctor and with their consent.
If you have any more questions, please do not hesitate to reach out.
I hope this helps.
Kind regards.
Was this conversation helpful?
Answered byDr. Manuel Moron
Medically reviewed byiCliniq medical review team
Same symptoms don't mean you have the same problem. Consult a doctor now!
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.