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Pelvic Inflammatory Disease - Causes, Symptoms, Treatment, and Prevention

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The article discusses pelvic inflammatory disease (PID), which is a common and serious infection of the female reproductive organs.

Medically reviewed by

Dr. Khushbu

Published At February 27, 2024
Reviewed AtMarch 5, 2024

What Is Pelvic Inflammatory Disease?

Pelvic inflammatory disease happens when the upper genital tract in women gets inflamed due to an infection. Typically, it begins with an infection in the lower genital tract and may subsequently impact the fallopian tubes, ovaries, and uterus. The primary cause of PID is typically sexually transmitted infections.

PID is most common among women aged 15 to 25 years. Doctors diagnose PID mainly based on symptoms like lower abdominal or pelvic pain and tenderness in the genital area. Treating PID involves using antibiotics to fight off the main bacteria, like gonorrhea and chlamydia. If left untreated, PID can lead to serious issues like abscesses in the pelvic area, infertility, or chronic pelvic pain.

What Causes Pelvic Inflammatory Disease?

Pelvic inflammatory disease is primarily caused by bacterial infections that affect the female reproductive organs. The most common causes of PID are sexually transmitted infections (STIs), particularly chlamydia and gonorrhea. However, other bacteria can also trigger PID.

Sexually Transmitted Infections:

  • Chlamydia trachomatis stands as a prominent contributor to PID. This bacterium can ascend from the vagina into the upper reproductive tract, leading to inflammation and infection of the uterus, fallopian tubes, ovaries, and cervix.

  • Neisseria gonorrhoeae, the bacterium responsible for gonorrhea, can also cause PID when it spreads to the upper reproductive organs.

  • Other STIs: Other sexually transmitted pathogens, such as Mycoplasma genitalium and Trichomonas vaginalis, have been implicated in PID, although less frequently.

Non-Sexual Transmission:

Sometimes, non-sexual transmission of bacteria can also contribute to PID development. Bacteria normally found in the lower genital tract can enter the upper reproductive organs through procedures like childbirth, abortion, or the insertion of intrauterine devices (IUDs).

What Factors Increase the Risk of Pelvic Inflammatory Disease?

The following factors are associated with an increased PID risk:

  • Women who are involved with multiple sexual partners.

  • Women with a history of STIs.

  • Teenagers and young individuals face elevated susceptibility to PID.

  • Recent pelvic procedures, like childbirth, abortion, or the insertion of IUDs, can elevate the risk of PID.

  • Douching disrupts the natural balance of vaginal bacteria, increasing the risk of PID.

  • Women who have had PID in the past are at higher risk of recurrent episodes.

  • Conditions that affect the cervix, such as cervical ectopy or cervical inflammation.

  • People with compromised immune systems, like those with HIV/AIDS or individuals receiving immunosuppressive therapy.

  • Using barrier methods inconsistently or incorrectly during sexual activity.

What Symptoms Indicate Pelvic Inflammatory Disease?

PID may not always present with obvious symptoms. It often manifests with subtle or mild symptoms, though in some cases, symptoms can be severe.

Common symptoms of pelvic inflammatory disease are:

  • Pain around the pelvis or lower tummy is a common symptom of PID.

  • Some individuals with PID may experience discomfort or pain deep inside the pelvis during sexual intercourse.

  • Pain or discomfort when urinating can be another symptom of PID.

  • Bleeding between periods or after sex, as well as heavier or more painful periods, may occur in individuals with PID.

  • PID can cause changes in vaginal discharge, particularly if it becomes yellow, green, or has a foul odor.

In severe cases, the following symptoms may occur:

  • Vomiting and nausea.

  • Intense pain in the abdomen.

  • A high temperature or fever.

How Is Pelvic Inflammatory Disease Diagnosed?

Diagnosing PID includes physical examination, laboratory tests, and imaging studies.

  • During a pelvic exam, doctors may observe signs of inflammation or tenderness.

  • Tests, including urine tests, blood tests, and swabs from the cervix or vagina, can help identify the specific bacteria causing the infection.

  • Imaging tests such as ultrasound or pelvic CT scans may be performed to look for complications such as abscesses or tubo-ovarian masses.

How to Treat Pelvic Inflammatory Disease?

The most common treatment for pelvic inflammatory disease is antibiotic therapy aimed at eliminating the underlying bacterial infection. A combination of antibiotics is often prescribed to cover a broad spectrum of pathogens. In instances of heightened severity or the emergence of complications, hospitalization may be necessary for intravenous antibiotic administration and close monitoring. In rare instances, surgical intervention may be needed to drain abscesses or remove damaged tissue.

When to See a Doctor for PID?

A doctor should be consulted immediately if a woman experiences severe symptoms of PID, like foul-smelling discharge from the vagina, severe lower abdomen pain, a high temperature, and nausea or vomiting. Even if the symptoms of PID are not severe, a doctor should be consulted. Signs such as vaginal discharge with an unpleasant odor, painful urination, or bleeding between menstrual periods might also signal an STI. Proper and timely treatment of an STI can help prevent PID.

What Are the Complications Associated With PID?

The potential complications of PID include,

  • Infertility - Untreated or poorly managed PID can lead to scarring and inflammation in the reproductive organs, particularly the fallopian tubes. Blockages and scarring within the fallopian tubes can impede the movement of eggs from the ovaries to the uterus, increasing the risk of infertility.

  • Chronic Pelvic Pain - Even after successful treatment, some women may experience persistent pelvic pain. The exact mechanisms underlying chronic pelvic pain in PID are not fully understood but may involve residual inflammation, nerve damage, or psychological factors.

  • Tubo-Ovarian Abscess Formation - In severe cases of PID, untreated infections can lead to the formation of abscesses in the fallopian tubes or ovaries. Tubo-ovarian abscesses are collections of pus that require immediate medical attention. Without timely intervention, abscesses can rupture, resulting in sepsis (a potentially serious systemic infection) or peritonitis (abdominal cavity swelling).

  • Ectopic Pregnancy - Damage to the fallopian tubes resulting from PID significantly elevates the risk of ectopic pregnancy. Research indicates that individuals who have experienced PID face a substantially higher risk of ectopic pregnancy compared to those without a history of PID.

How to Prevent Pelvic Inflammatory Disease?

Some tips can be followed to reduce the risk of PID.

  • Safe Sex - Consistently and correctly employing condoms during sexual intercourse can decrease the likelihood of acquiring STIs that can lead to PID.

  • STI Testing - Regular STI testing is advisable, particularly for individuals with more than one sexual partner or those engaging in high-risk sexual behaviors.

  • Sexual Partners - Limit the number of sexual partners to reduce the risk of exposure to STIs and subsequent development of PID.

  • Douching - Refrain from douching, as it can disturb the vaginal bacterial balance and heighten infection risk.

  • Contraceptive Options - Consult with doctors to explore contraceptive methods that minimize the risk of PID.

Conclusion

Pelvic inflammatory disease is a significant public health concern, impacting women's reproductive health and well-being. By understanding the causes, signs, treatment alternatives, potential complications, and preventive measures related to PID, individuals can take steps to safeguard themselves and reduce the burden of this condition. Raising awareness, teaching people, and making it easier to get healthcare help are important ways to reduce PID and its impact on people and healthcare systems.

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Dr. Khushbu
Dr. Khushbu

Obstetrics and Gynecology

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