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HomeAnswersHematologywhite blood cellsShould I do a bone marrow aspiration to find out why my WBC count is low?

What could be the reason for the low WBC count in an otherwise healthy female?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At February 10, 2023
Reviewed AtJanuary 5, 2024

Patient's Query

Hi doctor,

I am 40-year-old female with no symptoms, and in good physical condition. I typically have a blood test every year. I discovered that I had mild leucopenia at 3900/mm since the start of the year, but recently, my blood test has come back at 3600/mm. My differential counts are within the normal range. My hemoglobin is 12.7 g/dL, and I have mild Sjogren's syndrome, for which my doctor has said that no treatment is necessary. Due to inadequate ovarian reserve, I have no children, and my globulin is significantly higher (4.6 g/dl) on the LFT report. Due to subclinical hypothyroidism, I have been taking Thyronorm 50 mcg since last year. So my inquiry is, what comes next? My WBC is low; why? Do I need to rule anything with bone marrow aspirations?


Welcome to the icliniq.com,

You are having Sjogren's syndrome as per mentioned history.

Your leukocyte count is mildly low, which might be due to Sjogren's syndrome. Your peripheral smear examination report is normal and hemoglobin level and platelet count are also within limit.

So according to my opinion, there is no need for bone marrow aspiration study. So no need for further workup.

If dry mouth, joint pain, muscle pain and dry eye symptoms are troublesome then you can consult a rheumatologist for detailed evaluation and management.

I hope I have answered your question.

Let me know if I can assist you further.


Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri


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