What could be the reason for the low WBC count in an otherwise healthy female?

Question

Hi doctor,

I am a 40-year-old female with no symptoms and in good physical condition. I typically have a blood test every year. I discovered that I had mild leukopenia at 3900/mm since the start of the year, but recently, my blood test has come back at 3600/mm.

My differential counts are within the normal range. My hemoglobin is 12.7 g/dL, and I have mild Sjogren's syndrome, for which my doctor has said that no treatment is necessary.

Due to inadequate ovarian reserve, I have no children, and my globulin is significantly higher (4.6 g/dl) on the LFT report. Due to subclinical hypothyroidism, I have been taking Thyronorm 50 mcg since last year.

So my inquiry is, what comes next?
My WBC is low; why?
Do I need to rule out anything with bone marrow aspirations?

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

You are having Sjogren's syndrome as per the mentioned history.

Your leukocyte count is mildly low, which might be due to Sjogren's syndrome. Your peripheral smear examination report is normal, and your hemoglobin level and platelet count are also within limits.

So, in my opinion, there is no need for a bone marrow aspiration study. So no need for further workup.

If dry mouth, joint pain, muscle pain, and dry eye symptoms are troublesome, then you can consult a rheumatologist for a detailed evaluation and management.

I hope I have answered your question.

Let me know if I can assist you further.

Regards.