Sjogren's Syndrome

Sjogren’s syndrome or sicca syndrome is a triad of keratoconjunctivitis sicca, xerostomia, and rheumatoid arthritis. Dry eyes and mouth characterize this syndrome. Henrik Sjogren described it in 1933. It is an autoimmune disorder. It affects the mucous membranes of the eyes and mouth that lead to their decreased secretion. It also leads to generalized dryness.

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I have been having ear problems for the past three years. Please look at the MRI of my parotid glands to find any abnormality.

Query: Hi doctor, I have been having problems with my left ear for a few years. Around the same time, I became ill with POTS-type symptoms, but I am not sure if they are related to this query. I am experiencing pain, pressure, tinnitus, dizziness, and vertigo. I also have a globus sensation. I also have a ...  Read Full »


Dr. Akshay B K

Answer: Hello, Welcome to icliniq.com. Please do not worry; I understand your concern and will try and help you out. Please get back to me with the answers to the following questions so that we can arrive at a diagnosis. 1. The pain which is in the left ear, is it always present? Is there any ear discha...  Read Full »

I have autoantibodies in my blood and some related specific proteins. What could they indicate?

Query: Hello doctor, I have autoantibodies in my blood and some related specific proteins. I still do not have serious symptoms. I can send my results.  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I went through your post and investigations. There are a few significant results in the autoimmune profile. Your ANA (antinuclear antibody), dsDNA (double-stranded deoxyribonucleic acid), and anti-Ro are positive, which is suggestive of SLE (systemic lupus erythemato...  Read Full »

Do my eyes, throat, mouth, and nose become dry at night due to Sjogren's syndrome?

Query: Hello doctor, I am a 45-year-old male. I had a physical examination done ten months ago. My reports came normal. I began having dry eyes, dry throat, and mouth. My antibody test results came negative. My doctor said the ANA is a false positive, although I have lingering dryness of the throat, mouth,...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. You have dry eyes and mouth symptoms with positive ANA (antinuclear antibody) test. ANA is positive in 5 % of the general population and carries little significance unless associated with clinical symptoms. However, Sicca syndrome's symptoms need to be evaluated by sia...  Read Full »

Is Sjogren's syndrome the only cause for having dry eyes and dry mouth?

Query: Hi doctor, I am a 20-year-old male without a history of autoimmune disease in my family. But I have dry eyes and dry mouth for four months and I am unable to find the cause. I do not have dry eyes and mouth every day and it does not occur together. Recently, I also have joint pain while walking. ...  Read Full »


Dr. Reinhard Spyra

Answer: Hi, Welcome to icliniq.com. The provided information is not sufficient to establish a definite diagnosis. Kindly give some additional information regarding dry eyes and dry mouth. Please mention whether you experienced dry mouth daily for more than three months. Please mention whether you had any ...  Read Full »

Can I suffer from hepatitis C even if my hepatitis test reports are negative?

Query: Hello doctor, I recently had a complete lab test with my primary care provider in which my alanine transaminase (ALT) was 60 units per liter. My gamma globulin returned at 3.3 g/dL, and Sjogren's anti-SSA and anti-SSB levels were more than eight units per mL. The rheumatoid factor level was 34.2 IU ...  Read Full »


Dr. Mohamad Ali Rida

Answer: Hello, Welcome to icliniq.com. I doubt you have hepatitis C because the test is negative. It is common to have Sjogren's syndrome with positive anti-SSA (Sjogren's syndrome A), anti-SSB (Sjogren's syndrome B), and rheumatoid factor (RF). It all depends on your symptoms. Do you experience dryness in ...  Read Full »

Can I have lymphoma, kidney diseases, and eye problems due to secondary Sjogren's syndrome?

Query: Hello doctor, I have had dermatomyositis for three years and was asked to take tablet Cellcept. Before being diagnosed with dermatomyositis, I developed dry eye disease due to meibomian gland dysfunction. After taking the medicines, I had dryness in my mouth. I tested negative for anti-SSA Ro and an...  Read Full »


Dr. Mohamad Ali Rida

Answer: Hello, Welcome to icliniq.com. Do not worry, as you are receiving the best treatment for dermatomyositis. Secondary Sjogren's syndrome is a very common autoimmune disease. Being on tablet Cellcept (Mycophenolate mofetil 500 mg) is more than enough to prevent complications of Sjogren's syndrome. Yo...  Read Full »

My wife has Sjogren's syndrome and has been taking tablets Sulfasalazine. I am worried if it will impair her Type 1 interferon production. Please help.

Query: Hi doctor, My wife has had Sjogren's syndrome and related rheumatoid arthritis for about ten years. She has been experiencing a flare for five months now, which has migrated from her knees to her heel and hands. She is nearing 70. She is currently on tablet Sulfasalazine 500 mg, two in the morning a...  Read Full »


Dr. Sugreev Singh

Answer: Hi,Welcome to icliniq.com.I can understand your concern.It differs from person to person. Some people have a higher risk, while some do not. But since she has Sjogren's, I would suggest you continue with the same medicine and take precautions for COVID. Even if she stops the medication, there are ch...  Read Full »

I have dryness of eyes and mouth after taking antibiotics. Is it Sjogren's syndrome?

Query: Hello doctor,After a course of antibiotics, I have developed severe dry eyes, dry mouth, and photosensitivity. No tears are coming from my eyes. I think I have developed Sjogren's syndrome. Is there any treatment for Sjogren's? I am wating for the test. The antibiotics are long gone, but all the thi...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I went through your query. You have not mentioned which antibiotics you have taken. I do not think that you have Sjogren's. Firstly, one has to fulfill certain criteria for Sjogren's. Symptoms of dry eyes for more than three months. Symptoms of dry mouth for ...  Read Full »

Is Sjogren's syndrome same as SLE?

Query: Hi doctor,I have got a form of lupus called Sjogren's syndrome but I want to know if it is the same as SLE lupus or not as some hospitals say it is and some say it is not and I am very confused.  Read Full »


Dr. Lohit Chauhan

Answer: Hi, Welcome to icliniq.com. Sjogren's syndrome (SS) and SLE are two different forms of autoimmune inflammatory disorders which affect the joints, skin, glandular tissue. There are certain similarities between the two but generally, Sjogren's is characterized by decreased secretions from the lacrim...  Read Full »

What is the best treatment for the symptoms caused by Sjogren's syndrome?

Query: Hello doctor, According to my doctor, I have Sjorgen's syndrome. My big issue is that at times I have shortness of breath and it comes and goes. It used to happen not too often years ago, but now it happens every other month. Last year, I had to be hospitalized due to my racing heart which went t...  Read Full »


Dr. Amol Kumar Wasudeorao Diwan

Answer: Hello, Welcome to icliniq.com. From your description, it is clear that you have confirmed Sjogren's syndrome. Unfortunately, it is a chronic autoimmune disorder and treatment options are very limited. The treatment is only symptomatic and supportive in the sense that whatever symptoms you have we ...  Read Full »

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