Common "Sjogren's Syndrome" queries answered by top doctors | iCliniq

Sjogren's Syndrome

Sjogren’s syndrome or sicca syndrome is a triad of keratoconjunctivitis sicca, xerostomia, and rheumatoid arthritis. Dry eyes and mouth characterize this syndrome. Henrik Sjogren described it in 1933. It is an autoimmune disorder. It affects the mucous membranes of the eyes and mouth that lead to their decreased secretion. It also leads to generalized dryness.

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I have autoantibodies in my blood and some proteins. Why?

Query: Hello doctor, I have autoantibodies in my blood and some related specific proteins. I still do not have serious symptoms. I can send my results.  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to I went through your post and investigations. There are a few significant results in the autoimmune profile. Your ANA (antinuclear antibody), dsDNA (double-stranded deoxyribonucleic acid), and anti-Ro are positive, which is suggestive of SLE (systemic lupus erythemato...  Read Full »

I have Sjogren's syndrome with shortness of breath and increased heart rate. What should I do?

Query: Hello doctor,According to my doctor, I have Sjogren's syndrome. My big issue is that at times I have shortness of breath and it comes and goes. It used to happen not too often years ago, but now it happens every other month. Last year, I had to be hospitalized due to my racing heart which went to 18...  Read Full »

Dr. Amol Kumar Wasudeorao Diwan

Answer: Hello, Welcome to From your description, it is clear that you have confirmed Sjogren's syndrome. Unfortunately, it is a chronic autoimmune disorder and treatment options are very limited. The treatment is only symptomatic and supportive in the sense that whatever symptoms you have w...  Read Full »

Do all my symptoms occur due to lupus?

Query: Hi doctor,I am a 44-year-old female, and I have been diagnosed with rheumatoid arthritis, systemic lupus, and Sjogren's syndrome, with symptoms dating back to as young as six years old. I have also been diagnosed with pulmonary hypertension, thyroiditis, Raynaud disease, right-sided heart enlargemen...  Read Full »

Dr. Anshul Varshney

Answer: Hi, Welcome to The diagnosis of asthma is doubtful as pulmonary issues are seen in conditions you are already suffering from like SLE (systemic lupus erythematosus) and rheumatoid arthritis. Basically, the right term for you is MCTD (mixed connective tissue disease), which is ass...  Read Full »

Should I do a bone marrow aspiration to find out why my WBC count is low?

Query: Hi doctor, I am 40-year-old female with no symptoms, and in good physical condition. I typically have a blood test every year. I discovered that I had mild leucopenia at 3900/mm since the start of the year, but recently, my blood test has come back at 3600/mm. My differential counts are within the n...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to the, You are having Sjogren's syndrome as per mentioned history. Your leukocyte count is mildly low, which might be due to Sjogren's syndrome. Your peripheral smear examination report is normal and hemoglobin level and platelet count are also within limit. So accor...  Read Full »

Is my dry mouth because of my girlfriend's bronchiectasis?

Query: Hello doctor, I have a relationship with a girl, and she has bronchiectasis. She recently did bronchoalveolar lavage to collect the sample from the lungs for testing. The reports were negative for infection and malignancy, but there was an acute inflammation. Is this contagious? And my dentist said ...  Read Full »

Dr. Sugreev Singh

Answer: Hi, Welcome to I understand your concern. Her condition is contagious. If it was due to infection, we could say it is spreadable, but if the cause was hereditary or allergic, the chances of spreading are rare. Kindly answer the following questions to help you better; 1) Did you develop...  Read Full »

My wife has Sjogren's syndrome and takes Sulfasalazine. Advise.

Query: Hi doctor, My wife has had Sjogren's syndrome and related rheumatoid arthritis for about ten years. She has been experiencing a flare for five months now, which has migrated from her knees to her heel and hands. She is nearing 70. She is currently on tablet Sulfasalazine 500 mg, two in the morning a...  Read Full »

Dr. Sugreev Singh

Answer: Hi,Welcome to can understand your concern.It differs from person to person. Some people have a higher risk, while some do not. But since she has Sjogren's, I would suggest you continue with the same medicine and take precautions for COVID. Even if she stops the medication, there are ch...  Read Full »

Does herpes infection cause extreme dryness of mouth?

Query: Hello doctor, I have been struggling now with an issue for about a month. Extreme mouth dryness. Something very new to me. I have never had anything like this before. So sore mouth, sore tongue, and very dry. Is the case that I am short on saliva most definitely. I was recently tested for Diabetes ...  Read Full »

Dr. C. Elanchezhian

Answer: Hello, Welcome to Dry mouth due to reduced salivary gland secretion. Yes, herpes may be the reason for dryness affecting the glands. Are you under treatment for hypertension? For salivary flow, rinsing your mouth with warm salt water, sucking on sour lemons or sugar-free lemon candy ...  Read Full »

Is my extremely dry mouth due to the Botox treatment which I took two months ago?

Query: Hello doctor, I have an extremely dry mouth with no saliva at all. I have been seeing a rheumatologist because I thought the dry mouth was from Sjogren, and so did they. But I just got a lip biopsy which said it is not due to Sjogren. The only thing I can think of is that this all happened about one...  Read Full »

Dr. Kuljyot Bajaj

Answer: Hello, Welcome to Thank you for your query. May I please ask you a bit more about your symptoms? Has this been the first episode of dryness? If you think it is related to Botox injection, then how many days following injection did you start feeling dry mouth? What was the reason for ...  Read Full »

Can I have lymphoma, kidney diseases, and eye problems due to secondary Sjogren's syndrome?

Query: Hello doctor, I have had dermatomyositis for three years and was asked to take tablet Cellcept. Before being diagnosed with dermatomyositis, I developed dry eye disease due to meibomian gland dysfunction. After taking the medicines, I had dryness in my mouth. I tested negative for anti-SSA Ro and an...  Read Full »

Dr. Mohamad Ali Rida

Answer: Hello, Welcome to Do not worry, as you are receiving the best treatment for dermatomyositis. Secondary Sjogren's syndrome is a very common autoimmune disease. Being on tablet Cellcept (Mycophenolate mofetil 500 mg) is more than enough to prevent complications of Sjogren's syndrome. Yo...  Read Full »

Can I suffer from hepatitis C even if my hepatitis test reports are negative?

Query: Hello doctor, I recently had a complete lab test with my primary care provider in which my alanine transaminase (ALT) was 60 units per liter. My gamma globulin returned at 3.3 g/dL, and Sjogren's anti-SSA and anti-SSB levels were more than eight units per mL. The rheumatoid factor level was 34.2 IU ...  Read Full »

Dr. Mohamad Ali Rida

Answer: Hello, Welcome to I doubt you have hepatitis C because the test is negative. It is common to have Sjogren's syndrome with positive anti-SSA (Sjogren's syndrome A), anti-SSB (Sjogren's syndrome B), and rheumatoid factor (RF). It all depends on your symptoms. Do you experience dryness i...  Read Full »

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