The COVID-19 pandemic reminds us of the importance of immunization, which can save millions of lives. The newly approved, Johnson & Johnson COVID-19 vaccine, is a critical tool for fighting this global pandemic. To know more, have a look at this article.
Johnson & Johnson COVID-19 vaccine is a single dose vaccine developed by the Janssen Pharmaceutical Companies of Johnson & Johnson to prevent COVID-19. It is the third COVID-19 vaccine that got approved after the two-shot regimens of Pfizer- BioNtech and AstraZeneca, and it is the first single-dose vaccine.
The data from the Phase 3 ENSEMBLE study shows that this vaccine is 85% effective in preventing COVID-19. It provides protection 28 days after the vaccination. The Johnson & Johnson company is planning to apply for the Biologics License Application with the FDA. It uses the AdVac vaccine platform, which is a unique technology that was used to develop Janssen’s European Commission-approved Ebola vaccine.
The study was enabled to understand the safety and efficacy of this COVID-19 vaccine in protecting against both moderate and severe cases. The efficacy was evaluated on day 14 and day 28 after vaccination.
Johnson & Johnson vaccine is compatible with standard vaccine storage and distribution channels with ease of delivery to remote areas. The vaccine remains stable for two years at -4 degree F (-20 degree Celsius) and a maximum of three months at temperatures of 36 to 46 degree F (2 to 8 degree Celsius). The vaccine should not be re-frozen if distributed at a temperature of 36 - 46 degrees F (2 to 8 degrees Celsius).
Johnson & Johnson COVID-19 vaccine is recommended for individuals of age 18 years and above.
Individuals who have a severe allergic reaction to any of the ingredients of this vaccine.
Johnson & Johnson vaccine is a single-dose vaccine. It is administered intramuscularly in the deltoid muscle.
Before getting vaccinated, you have to inform if you:
Have any allergies.
Have any bleeding disorders.
Are on any blood thinners.
Are pregnant or breastfeeding.
Have received another COVID-19 vaccine earlier.
Pfizer and Moderna require two shots to get the maximum protection against the COVID-19. But in the case of the Johnson & Johnson vaccine, it is a single-shot vaccine. If you are worried about the side effects, you should go for the Johnson & Johnson vaccine, as the side effects are minimal compared to Pfizer and Moderna vaccines. According to Pfizer, about 3.8% of their clinical trial participants experienced fatigue and 2% experienced headaches. According to Moderna, 9.7% of the trial participants experienced fatigue and headache. According to the Centre for Disease Control and Prevention, the side effects from the second shot will be more than the first shot.
In trials of both Pfizer and Moderna, more people experienced side effects after the second shot. You are bound to get the second shot even if you experience side effects from the first shot. The main side effects of the Johnson & Johnson vaccine are pain at the injection site and flu-like symptoms.
In Pfizer and Moderna vaccines, mRNA is introduced into your body, unlike the traditional vaccines where a weakened or inactivated germ is injected into the body. The mRNA is a code that serves as an instruction manual to the immune system to identify the virus and attack it. In the case of the Johnson & Johnson vaccine, instead of using mRNA, it uses a disabled adenovirus to provide the instructions on how to attack the virus.
Yes, the biggest advantage is that Johnson & Johnson COVID-19 vaccine can be kept at refrigerator temperatures for months, and it will be stable. In contrast, Pfizer and Moderna vaccines are not as stable as Johnson & Johnson vaccine, and they require very cold storage temperatures. Once Pfizer and Moderna are taken out of cold temperatures, their window time is short, but it is not the case in Johnson & Johnson vaccine. Hence it is better to maintain and deliver to different parts of the country, especially for the rural areas.
The side effects that have reported include :
Redness of the skin around the injection site.
Swelling at the injection site.
There can be general side effects like other vaccines have:
There is also a report saying that there can be severe allergic reactions.
The signs of a severe allergic reaction include:
Swelling of the face.
Rashes all over the body.
These signs are not the expected side effects. But when serious these unexpected side effects may occur. The clinical trials of the Johnson & Johnson vaccine are still being studied.
Johnson & Johnson Covid-19 vaccine has high efficacy in preventing hospitalization and death in people who get sick. No one who got COVID-19 after getting vaccinated with Johnson & Johnson COVID-19 vaccine was hospitalized.
There is also evidence saying that Johnson & Johnson Covid-19 vaccine provides protection against asymptomatic infection.
Johnson & Johnson Covid-19 vaccine was 66.3% effective in the clinical trials at preventing COVID-19 infection in people who had no evidence of the prior COVID-19 infection.
People had the maximum protection against the COVID-19 infection after two weeks of vaccination.
The Federal Health Authorities recommended temporarily stopping the Johnson & Johnson vaccine while they were investigating a potential link to the very rare blood clots. CDC and FDA are reviewing the six reported cases of rare and severe types of blood clots that developed after getting vaccinated. Hence there is a temporary pause in administering the vaccine.
No vaccine can be 100% effective. The only thing is that it reduces the severity of the disease. That is the most important factor from a vaccine. Johnson & Johnson COVID-19 vaccine was 85% effective in preventing hospitalizations and death. So, if you have access to get any vaccine, you should get it. Even if it is not 100% effective, you are less likely to have severe disease.
Last reviewed at:
26 Apr 2021 - 4 min read
Article Overview: Highly crowded public places, such as amusement parks and movie theatres, can result in the rapid spread of COVID-19 infection. Learn how to protect yourself in such places. Read Article
Overview: We visit amusement parks, carnivals, and similar places with our children for leisure and entertainment. With the ongoing pandemic, such highly crowded public places can result in the rapid spread of COVID-19 infection. To prevent this spread, you should follow physical distancing and oth... Read Article
Article Overview: A COVID-19 vaccine provides acquired immunity against the new Coronavirus. Read the article to know everything about the approved and undertrial vaccines. Read Article
Many pharmaceutical companies worldwide are working on potential vaccines for the new Coronavirus disease (COVID-19). With COVID-19 cases continuing to grow, scientists and doctors are working day and night to develop vaccines to slow the pandemic and lessen its damage. How COVID-19 Vaccines Work? ... Read Article
Most Popular Articles
Do you have a question on Covid-19 or Covid-19 Vaccine?Ask a Doctor Online