ALT, alanine transaminase, is an enzyme made by the cells in the liver which gets released into the bloodstream if the liver is inflamed or damaged. An ALT test will help to measure the amount of ALT in the blood. The normal range lies between 29 to 33 IU/L (international units per liter) for males and 19 to 23 IU/L for females. High levels of ALT in the blood indicate liver problems such as hepatitis, cirrhosis, liver cancer, or other issues.

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What causes the rise of ALT and HDL in blood?

Query: Hi doctor, I am a 46-year-old man of 5.9 feet height and 194 lbs weight. My T4 is 11.39 ug/dL, TSH is 0.005 uIU/mL, and HDL is 34.30 mg/dL, creatine serum is 0.78 mg/dL, ALT serum is 60.90 u/L. I am attaching my reports. Kindly give your opinion.  Read Full »

Dr. Shaikh Sadaf

Answer: Hello, Welcome to I just read your query and the reports that you have attached (attachments removed to protect the patient's identity). It appears that you have hyperthyroidism. It means that your thyroid gland is hyperfunctioning. Before we proceed with any treatment, you must do: ...  Read Full »

What causes severe abdominal pain with raised AST and ALT levels in an 8-year-old kid?

Query: Hello doctor, My 8-year-old daughter continues to have strong abdominal pains. A couple of months before, it was really bad and was also coupled with mono and fifths disease. At that time her levels were crazy high. AST = 1312, ALT = 1692. These levels freaked out the doctors so we went back the nex...  Read Full »

Dr. Deepak Patel

Answer: Hi, Welcome to I can understand your concerns. This appears to be a case of obstructive jaundice. The main cause of obstructive jaundice is gallstones. Since GGT (gamma-glutamyl transferase) levels are raised more than 70 in the first report it suggests an obstructive cause. AST (aspa...  Read Full »

Are my blood report results showing something serious?

Query: Hello doctor,I recently had my annual exam done and have had some odd results. Vitamin B12 was over 2000 ng/ml ref range was 200 to 1100. I do not take any b12 or multivitamins. Globulin was 1.8 g/dl ref range 1.9 to 3.7. The albumin/globulin ratio 2.7 range was 1.0 to 2.5. AST 41 u/l ref range was ...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to Your B12 level is very high. Liver disease, kidney disease, myeloproliferative blood neoplasm, etc., are some of the causes for elevated B12. Your ALT (alanine transaminase) is high, so for liver disease do further work up in form of USG abdomen and viral marker study....  Read Full »

I have been experiencing raised ALT levels and abdominal pain after working with CCl4. Is this pain due to CCl4 exposure?

Query: Hello doctor, I had to work with carbon tetrachloride (CCl4) twice a week for three months for my project, and I used all the necessary protection but I got abdominal pain. The doctor examined it and the sonography showed coarse parenchyma and ALT was raised by 10 units. I have pain in my right uppe...  Read Full »

Dr. Sagar Ramesh Makode

Answer: Hello, Welcome to Are you an alcoholic, or do you smoke? Are you sure the ultrasound is showing any coarse echo texture? Please get it reviewed once since the echo texture is not usually coarse. Was there any fatty liver? Your current problem looks like gastritis and acidity proble...  Read Full »

Please suggest ways to lower SGPT levels.

Query: Hi doctor, My daughter is 8 years old. She is suffering from jaundice for the past four months. Presently, as per her blood test, bilirubin 0.40 mg/dL, conjugated bilirubin 0.10 mg/dL, unconjugated bilirubin 0.30 mg/dL and ALT (SGPT) 57.00 U/L. The medicines she had been prescribed are Junior Lanzol...  Read Full »

Dr. Faisal Abdul Karim Malim

Answer: Hello, Welcome to To add to your knowledge, SGPT is a marker of inflammation of the liver (serum glutamic-pyruvate transaminase). Whenever there is some damage to the liver, the SGPT will rise along with serum bilirubin levels. During healing of the liver, the SGPT levels slightly raise...  Read Full »

My ALT and AST levels are high and found fat on my liver ultrasound. What should I do?

Query: Hello doctor, I am 42 years male with controlled hypertension. I did my annual check-up, and I found ALT and AST are 192 and 142, which are elevated. I had an ultrasound, and I found fat from marked to moderate on my liver. Lipid profile results are in the optimal level, CBC and kidney results also...  Read Full »

Dr. Muhammad Majid Hanif

Answer: Hello, Welcome to Certain prescription and over-the-counter drugs may also cause increased liver enzyme levels. In studies, we have seen that Candesartan (Atacand 8 mg) that you are taking, can cause deranged hepatic function and also inflammation of the liver (hepatitis) to some exte...  Read Full »

What does high value of ALT, AST, and ALP indicate?

Query: Hello doctor, I want to show my LFT report. I was suffering from jaundice. In my first test result total bilirubin was 11.2 mg/dL (D: 2.1, ID: 9.1), and the values of ALT, AST, and ALP are 53, 41, and 162 u/l, respectively. Hepatitis B was negative. In my second test results, the total bilirubin c...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I can understand your concern and the following is my opinion about your asked question. ALT (alanine transaminase) or SGPT (serum glutamic pyruvic transaminase) is the liver cells' enzyme. So, raised the level of which is suggestive of liver cell (hepatocyte) damag...  Read Full »

My mom is diagnosed with autoimmune hepatitis with high ALT and AST levels. Please help.

Query: Hello doctor, My mom was diagnosed by chance with the liver disease about three months ago when she did some routine blood tests. Her values then were: ALT = 157 U/L. AST = 106 U/L. ALP = 727 U/L. GGT = 575 U/L. She had ultrasound and CT tests, but nothing wrong showed up with her liver at all. She...  Read Full »

Dr. Ghulam Fareed

Answer: Hello, Welcome to I read your query and can understand your concern. I am reviewing your case history in detail and will get back to you shortly. Thanks and take care.  Read Full »

My SGPT ALT test shows a value of 13 U/L. What does it indicate?

Query: Hello doctor, My SGPT ALT test shows a value of 13 compared to the recommended value of 16 to 63 U/L.What does it indicate? I have chronic constipation. Kindly help.  Read Full »

Dr. Ghulam Fareed

Answer: Hello, Welcome to Thank you for your query. I understand your concern. I have reviewed your attached reports, and ALT is slightly below the normal range. But there is nothing to be worried about. Liver function tests are usually checked to see whether they are raised. Increased level...  Read Full »

Could cocaine use two days before blood draw cause the LFTs to be elevated?

Query: Hello doctor, Could cocaine use two days before blood draw cause the LFTs (ALT=90 and AST=86) to be elevated? If so, how long of an abstinence period (not using cocaine) would be needed to get LFTs back down to normal levels?  Read Full »

Dr. Vivek Chail

Answer: Hi, Welcome to I have read through your query in detail. Please find my observations below. Taking cocaine two days earlier can increase the LFTs. LFTs can also be raised due to many causes including liver infection, increased alcohol intake, intake of toxic chemicals including cocaine,...  Read Full »

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