Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis or ALS is a degenerative motor neuron disease, meaning, it affects the nerve cells. The brain loses control over the voluntary muscles, causing inability to move around, speak, eat and eventually even breathe. Early symptoms include muscle twitching, weakness of legs and arms, and speech difficulties. Currently, there is no cure for this disease.

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I have been experiencing on and off muscle twitching for the past two years. Please help.

Query: Hello doctor, I have been having on and off muscle twitching for the past two years, and having no other symptoms. Could this still be slow progression ALS?  Read Full »

Dr. Hitesh Kumar

Answer: Hi, Welcome to I understand your concern. I would like to know some details about your symptoms: 1. In which body parts, do you have twitching? 2. Are these twitching visible to the eyes? Or only felt inside? 3. Have you noticed any weakness or thinning of some part of arm or leg ...  Read Full »

Are tingling in hands and legs due to carpal tunnel or ALS?

Query: Hello doctor, I have tingling in my hands for a few years, and now I am feeling tingling off and on in my feet and legs with occasional inner tremors. I had all my blood work done to test for diabetes, thyroid, vitamin deficiency, CMP and CBC all came back normal. I had an MRI of the brain that cam...  Read Full »

Dr. Anshul Varshney

Answer: Hi, Welcome to These symptoms do not look like ALS (amyotrophic lateral sclerosis). Moreover, carpal tunnel syndrome (CTS) has been established in your reports. Anxiety and CTS are more than enough to cause these symptoms. So, my recommendation is that you should start on Pregabalin 7...  Read Full »

I am experiencing burning sensations in the back and feet with muscle twitches throughout the body. Could it be ALS?

Query: Hello doctor, I am worried that I have ALS (amyotrophic lateral sclerosis). Three weeks ago, I had an episode of nerve pain. Burning in the back, feet, etc. Sometimes it feels like I have ice on my back. I also had shooting pain in several areas of my body, like an electrical shock. A couple of days...  Read Full »

Dr. Seyedaidin Sajedi

Answer: Hello, Welcome to I reassure you that your symptoms do not suggest ALS (amyotrophic lateral sclerosis). ALS is a motor disease that does not cause any sensory problems. Moreover, it is a slowly progressive disease that almost always initiates from one limb and slowly progresses to ano...  Read Full »

I have been experiencing twitching in different body parts, but now I have twitching in my stomach too. Can this be a sign of ALS?

Query: Hello doctor, I am an anxious guy and often have twitching in different parts of my body. But now I can feel twitching in my stomach too. I read that this is not common and could be an early sign of ALS. Do I need to worry?  Read Full »

Dr. Seyedaidin Sajedi

Answer: Hello, Welcome to Thank you for your query. I suggest you to give me a few more details: How long do you have these muscle twitches? Do you have weakness or muscle wastage (atrophy) in any limb, especially in distal parts of the hands or feet? Thank you.  Read Full »

Apart from ALS, which other conditions cause muscle twitching?

Query: Hi doctor, I am a 24 year old female. For the last three days, I have noticed continuous twitches on the thenar aspect of my right palm. Today, I searched on the internet and it showed it could be ALS. I am worried. Also, I noticed that my right thenar prominence is a little less than the left. I do...  Read Full »

Dr. Hardik Nareshbhai Rajyaguru

Answer: Hi, Welcome to I do not think this to be ALS (amyotrophic lateral sclerosis). ALS will have little more extensive twitches and at times they are visible on the muscle surface and a number of muscles having the flaccid type of weakness. Fasciculation only for three days without an...  Read Full »

I have muscle twitching in my arms, elbows, and nose bridge. Is it a symptom of ALS?

Query: Hello doctor, I am a 37-year-old man. A few years ago, I had terrible anxiety attack and had some strange symptoms like hand tingling and hand cramp, followed by muscle twitching in my arms around the back of my elbows and other twitching. I wondered whether this could be the start of ALS. I think I...  Read Full »

Dr. Nene Devavrat Harihar

Answer: Hello, Welcome to After reading through your history, it seems you have some twitching over your entire body without weakness and some sensory symptoms of short duration. All of these point away from ALS (amyotrophic lateral sclerosis). This can be benign fasciculation syndrome or mig...  Read Full »

I have had leg weakness and discomfort for a few months. Are there possibilities that I have multiple sclerosis or amyotrophic lateral sclerosis?

Query: Hi doctor, Since few months, I have had leg weakness, but they are not actually weak. They just feel like it. And also feels heavy sometimes. I also have slight shakiness in hands and shooting pains in my left knee. The cardiology checkup was normal, CT scan done a month ago was normal except for an...  Read Full »

Dr. Hitesh Kumar

Answer: Hello, Welcome to I would like to know some details about your symptoms: 1. since when do you have the symptoms? How long was the duration? Was it of sudden onset or developed slowly over time? 2. How exactly do you feel in your legs? What activities seem difficult with legs - getti...  Read Full »

What is the chance of getting ALS if someone in the family had it?

Query: Hello doctor,My grandfather died of ALS, and now I am having signs of it. He is the only one that we know of that had it in the family. So my first question is, what are the chances of me getting it? The second question is I twitch in my left arm, left hand, left leg, and left calve non-stop. Someti...  Read Full »

Dr. Mahmoud Ahmed Abdelrahman Abouibrahim

Answer: Hello, Welcome to I understand your concerns. ALS (Amyotrophic lateral sclerosis) is familial in only 10 % of the cases. The diagnosis is mainly clinical (with characteristic symptoms). EMG and NCS (nerve conduction studies) may help in the diagnosis, symptoms include: 1. Fascicula...  Read Full »

Should I get electromyography to rule out amyotrophic lateral sclerosis?

Query: Hello doctor, For the last few days, I have had fasciculations in my calves and muscle cramps in my leg, especially after training. Sometimes, I feel some numbness in my right arm. I am really concerned about ALS, and my doctor says that I do not need EMG. What is your opinion about it? Kindly sugge...  Read Full »

Dr. Aida Abaz Quka

Answer: Hello, Welcome to I understand your concern and can explain that cramps in ALS (amyotrophic lateral sclerosis) usually occur at an advanced stage when there is muscle weakness and muscle wasting. So, I do not think that this is your case. Dehydration can lead to this clinical situation‚...  Read Full »

Does twitching in the calf muscle mean I have amyotrophic lateral sclerosis?

Query: Hello doctor, I am a 25-year-old female and I am afraid I have ALS. This¬†started with twitching in my right calf muscle two months ago and that has now spread to everywhere. A clinical exam showed slightly asymmetrical¬†brisk knee reflex, and it is brisker on the right leg where it bothers me, not ...  Read Full »

Dr. M. A. Toyeb, Nazma Parveen

Answer: Hello, Welcome to I can completely understand your concern. First of all, ALS (amyotrophic lateral sclerosis) is a condition which requires time to diagnose especially when it is in the initial stages. You said you experience twitching in your muscles. Do you have any other problem...  Read Full »

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