Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis or ALS is a degenerative motor neuron disease, meaning, it affects the nerve cells. The brain loses control over the voluntary muscles, causing inability to move around, speak, eat and eventually even breathe. Early symptoms include muscle twitching, weakness of legs and arms, and speech difficulties. Currently, there is no cure for this disease.

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I have had leg weakness and discomfort for a few months. Are there possibilities that I have multiple sclerosis or amyotrophic lateral sclerosis?

Query: Hi doctor, Since few months, I have had leg weakness, but they are not actually weak. They just feel like it. And also feels heavy sometimes. I also have slight shakiness in hands and shooting pains in my left knee. The cardiology checkup was normal, CT scan done a month ago was normal except for an...  Read Full »

Dr. Hitesh Kumar

Answer: Hello, Welcome to I would like to know some details about your symptoms: 1. since when do you have the symptoms? How long was the duration? Was it of sudden onset or developed slowly over time? 2. How exactly do you feel in your legs? What activities seem difficult with legs - getti...  Read Full »

What is the chance of getting ALS if someone in the family had it?

Query: Hello doctor,My grandfather died of ALS, and now I am having signs of it. He is the only one that we know of that had it in the family. So my first question is, what are the chances of me getting it? The second question is I twitch in my left arm, left hand, left leg, and left calve non-stop. Someti...  Read Full »

Dr. Mahmoud Ahmed Abdelrahman Abouibrahim

Answer: Hello, Welcome to I understand your concerns. ALS (Amyotrophic lateral sclerosis) is familial in only 10 % of the cases. The diagnosis is mainly clinical (with characteristic symptoms). EMG and NCS (nerve conduction studies) may help in the diagnosis, symptoms include: 1. Fascicula...  Read Full »

Should I get electromyography to rule out amyotrophic lateral sclerosis?

Query: Hello doctor, For the last few days, I have had fasciculations in my calves and muscle cramps in my leg, especially after training. Sometimes, I feel some numbness in my right arm. I am really concerned about ALS, and my doctor says that I do not need EMG. What is your opinion about it? Kindly sugge...  Read Full »

Dr. Aida Abaz Quka

Answer: Hello, Welcome to I understand your concern and can explain that cramps in ALS (amyotrophic lateral sclerosis) usually occur at an advanced stage when there is muscle weakness and muscle wasting. So, I do not think that this is your case. Dehydration can lead to this clinical situation‚...  Read Full »

Does twitching in the calf muscle mean I have amyotrophic lateral sclerosis?

Query: Hello doctor, I am a 25-year-old female and I am afraid I have ALS. This¬†started with twitching in my right calf muscle two months ago and that has now spread to everywhere. A clinical exam showed slightly asymmetrical¬†brisk knee reflex, and it is brisker on the right leg where it bothers me, not ...  Read Full »

Dr. M. A. Toyeb, Nazma Parveen

Answer: Hello, Welcome to I can completely understand your concern. First of all, ALS (amyotrophic lateral sclerosis) is a condition which requires time to diagnose especially when it is in the initial stages. You said you experience twitching in your muscles. Do you have any other problem...  Read Full »

My partner had an electric shock a year ago and still has a shock-like feeling and pain. Why?

Query: Hello doctor, My partner got an electric shock to his right arm a year ago. Ever since then, he has felt like he is constantly shocked, and he has been unable to move his arm properly. He is on 750 mg of Lyrica a day to control the shock-like feeling and pain. However, the hand movement has not retu...  Read Full »

Dr. Ramesh Kumar S

Answer: Hi, Welcome to Cases of motor neuron disease are seen after electric shocks. Most likely, your partner is experiencing wasting of muscles due to motor neuron disease post the electric shock. A motor neuron (or motoneuron) is a nerve cell, which directly or indirectly controls the...  Read Full »

How can I rule out ALS?

Query: Hi doctor, About five weeks ago, I started feeling some weakness in my left leg. I have consulted my family doctor and a neurologist. All physical tests showed no actual weakness. There were no other clinical signs and the reflexes were also normal. There is no activity or movement that I cannot do....  Read Full »

Dr. J. Mariano Anto Bruno Mascarenhas

Answer: Hi, Welcome to The various symptoms you have described are due to L5-S1 moderate broad left paracentral disc protrusion mildly distorted the anterior aspect of the thecal sac and abutting without displacing the traversing nerve roots. When a disc prolapses and compresses the spinal c...  Read Full »

I am 51 years old and have been experiencing muscle twitching. Please suggest some treatment for the same.

Query: Hello doctor, I am 51 years old and have been experiencing muscle twitches several times an hour for almost three to four weeks. I have had no muscle weakness or imbalance. Sometimes, I experience sharp pain, but the muscle twitches last only a few seconds. They happen anywhere on my body, including...  Read Full »

Dr. Abhaya Kant Tewari

Answer: Hello, Welcome to Thank you for the detailed history. Your reports (attachments removed to protect the patients' identity) suggest that you are suffering from simple benign fasciculation syndrome, characterized by random twitching of muscles affecting various body parts. There is no p...  Read Full »

I have twitching of different muscles. Can I be sure it is not ALS?

Query: Hello doctor, The last week and a half every few minutes, I got a muscle twitch in random parts of my body. My left eye twitches more constantly than that. I have general anxiety and major health anxiety which I am wondering can play a role. I have no muscular weakness at all, and no atrophy from wh...  Read Full »

Dr. Hitesh Kumar

Answer: Hello, Welcome to Frequent muscle twitches without any muscle weakness or atrophy and normal reflexes can be due to anxiety. The other possibility can be benign fasciculation syndrome. But before labeling this, it is advisable to rule out other possible grave diseases. Let me suggest...  Read Full »

Where are my symptoms leading to?

Query: Hi doctor, My symptoms over the last four months are as follows. I sat down on my mother's bed and could not get up. I had severe pain in lower back on left side shooting down my leg. They felt like electric shocks and it lasted for a little over a week. During that time I had a lot of memory issue...  Read Full »

Dr. Anshul Varshney

Answer: Hello, Welcome to These all symptoms could be unrelated but can be related too. In my opinion, you should be evaluated for multiple sclerosis. A person with ALS (amyotrophic lateral sclerosis) or multiple sclerosis (MS) can have almost any neurological symptom or sign. Autono...  Read Full »

Are my muscle twitching and spasm due to ASL?

Query: Hi doctor, I think I have ALS; what are the symptoms of it? I have been experiencing muscle twitching and spasm for over a month, and I am scared of having ALS. Please help me with this issue.  Read Full »

Dr. Aida Abaz Quka

Answer: Hello, Welcome to I understand your concern and would explain that muscle twitching is a very common symptom related to many metabolic causes like high caffeine intake, dehydration, thyroid gland dysfunction, vitamin D or vitamin B12 deficiency, insomnia, etc. But when muscle twitchin...  Read Full »

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