What causes ankylosing spondylitis?

Question

Hello doctor,

I am a 38-year-old male who was diagnosed with ankylosing spondylitis two years ago. I have been struggling with pain and stiffness, which makes it difficult to perform daily tasks such as walking, bending, and even sitting for extended periods. I am very curious about what caused this condition and whether there is any specific trigger that led to the development of ankylosing spondylitis. Why has this happened to me? Could you help me understand the root cause and any possible underlying factors? Is there a way to manage this condition? I am seeking guidance on how to improve my situation.

Kindly help.

Thank you.

Answer 1

Hello

Welcome to icliniq.com.

I understand your concern.

Ankylosing spondylitis, also referred to as axial spondyloarthritis, is an inflammatory disease that, over time, can cause some of the bones in the spine, known as vertebrae, to fuse. This fusion reduces the flexibility of the spine and may result in a hunched posture. If the ribs are affected, deep breathing may become difficult.

As ankylosing spondylitis progresses, new bone formation occurs as part of the body's attempt to heal. This new bone gradually bridges the gaps between vertebrae and eventually fuses sections of the vertebrae. Fused vertebrae can flatten the natural curves of the spine, leading to an inflexible, hunched posture.

Axial spondyloarthritis can be classified into two types. When the condition is visible on X-rays, it is referred to as ankylosing spondylitis, a form of axial spondyloarthritis. When the condition cannot be detected on X-ray but is diagnosed based on symptoms, blood tests, and other imaging tests, it is referred to as non-radiographic axial spondyloarthritis.

Symptoms generally begin in early adulthood. Inflammation may also occur in other parts of the body, with the eyes being the most commonly affected.

Although there is no cure for ankylosing spondylitis, treatments are available that can alleviate symptoms and may help slow the progression of the disease.

I hope that you get your answer.

Please, let me know if you want some help.

Thank you.