Common "Ankylosing Spondylitis" queries answered by top doctors | iCliniq

Ankylosing Spondylitis

Ankylosing spondylitis is an autoimmune inflammatory disorder of the spine characterized by pain and stiffness with a variable course. It mainly affects the joints of the spine and sacroiliac joint in the pelvis. As the severity increases, the joints start to fuse with each other resulting in a rigid spine.

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Please suggest medicine for stiffness caused by ankylosing spondylitis.

Query: Hi doctor,I have been diagnosed to have ankylosing spondylitis approximately 2 years back. I also had psoriasis, probably due to the same and it is chronic. Of late, there is extreme pain and even more stiffness, especially during the morning. It is no more tolerable and hence I am writing this. I a...  Read Full »

Dr. Sumit Chawla

Answer: Hello, Welcome to Here are the answers to your questions. You have been diagnosed as a case of ankylosing spondylitis with psoriasis. Both the condition will affect your joints. Ankylosing will affect mainly axial skeletal joints. Psoriasis mostly affects peripheral joints and is of ...  Read Full »

Is rheumatoid factor a genetic disorder?

Query: Hello doctor,I have a question relating to my deceased father. I obtained his medical records after his death. While searching through his records to gain a better understanding of what may happen to me, I found he was positive for the rheumatoid factor and had been diagnosed with ankylosing spondyl...  Read Full »

Dr. Naval Mendiratta

Answer: Hello, Welcome to Well, I do not think you should be worried about anything. Firstly rheumatoid factor is not transmitted genetically unlike HLA- B27 (human leucocyte antigen). Secondly, it can be positive in a lot of people but does not cause any symptoms. Thirdly, you have been test...  Read Full »

I am a HLA B27-positive male. Will it pass to my children?

Query: Hello doctor, I am a 26-year-old, and I had hip resurfacing surgery eight years back. I am an HLA B27 positive, even my father is also positive. I have had joint pain for the last fourteen years. Now, I wish to know that if I marry and have children will this pass on to them? What measures should I...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to About 80 % of people with ankylosing spondylitis have HLA B27 positive, and only 1 to 4 % of people with positive HLA B27 develop ankylosing spondylitis. That means out of 100 people with positive HLA B27, only one to four can develop ankylosing spondylitis, and 96 t...  Read Full »

Is biologic Etanercept suitable for my ankylosing spondylitis?

Query: Hello doctor,I have ankylosing spondylitis (HLA B27 positive) for the past 12 years and with pulmonary tuberculosis the very next year. And took medicine for nine months, and now I am daily taking Saaz, and I am going to plan for Biologics. The doctor suggested Etanercept 50 mg, but I am afraid of s...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to You need to do Mantoux test and interferon gamma level before starting biologics because they can cause reactivation of tuberculosis if there is doubt you should receive the two drug ATT regimen (anti-tubercular treatment) before starting biologics that is recommend...  Read Full »

Can my husband take Adalimumab for ankylosing spondylitis?

Query: Hello doctor,My husband is suffering from ankylosing spondylitis, and he is under treatment since last year. His doctor has now suggested Adfrar 40 injections along with physiotherapy and a belt. The doctor has also suggested halting swimming until further instructions. I am looking for a second opi...  Read Full »

Dr. Naval Mendiratta

Answer: Hello, Welcome to I have gone through your reports (attachment removed to protect the patient's identity), and his disease does look quite severe. Developing a compression fracture is an indication that the disease activity is high. The reason for stopping exercises would be the f...  Read Full »

How do I overcome muscle and nerve tightening? Please help.

Query: Hello doctor, Seven years ago, I was affected by ankylosing spondylitis (HLA-B27 positive) (RF negative). And then after a year, I was affected by pulmonary tuberculosis (TB lungs). Tuberculosis was controlled within months and I continued taking medication for ankylosing spondylitis. And then f...  Read Full »

Dr. Anshul Varshney

Answer: Hi, Welcome to Following are the answers for your queries: Get an  MRI LS spine done, to see for any disc prolapse as the pain you are describing along with tingling sensation is seen in disc prolapse only. A combination of Pregabalin and Methylcobalamine will help you in neuropathy pa...  Read Full »

I have been experiencing severe pins and needles sensation in my palms and feet. Please help.

Query: Hi doctor, I am having a pins and needles sensation in my palms and feet. Also, stinging pain can be felt when performing physical activities that involve the upper body. X-ray report of the thoracic spine mentions potential ankylosing spondylitis due to the presence of interspinous ligament ossific...  Read Full »

Dr. Muhammad Shoyab

Answer: Hi, Welcome to I understand your concern. I understand it is quite concerning to have apparently dissimilar reports on two tests, especially when you are having specific and persistent symptoms. However, the good news is that MRI (magnetic resonance imaging) is almost the gold standa...  Read Full »

I am suffering from ankylosing spondylitis. Kindly help.

Query: Hello doctor,I am suffering from ankylosing spondylitis from two years. Can you please tell me whether there are chances to slow the disease progression and how?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to There are four modes of therapy for ankylosing spondylitis. NSAID (non steroidal anti inflammatory drugs) group, steroid, disease-modifying anti-rheumatic drugs such as Methotrexate, TNF blocker like Adalimumab, physiotherapy also should be done, also avoid smoking, m...  Read Full »

I am suffering from ankylosing spondylitis. Kindly help.

Query: Hello doctor,I am suffering from ankylosing spondylitis (HLA B27 positive and Rh factor negative) for 10 years, now on Saaz-DS, SI joints are fused. Movement restrictions of the neck, forward bending, and morning stiffness with sciatica. Kindly suggest new medications and NSAIDs. I have attached HLA...  Read Full »

Dr. Puri Divya Inder

Answer: Hello, Welcome to The NSAIDs you can take are Etoricoxib 90 mg once daily orDiclofenac75 mg twice daily. You can try this out and see which one helps more. Once your pain is controlled, you can try to reduce the dose to alternate days or even lesser depending on your pain. Folic acid ...  Read Full »

Why did the pain on the right side of my back move to the hips?

Query: Hi doctor,I have pain in my hips. I began to have a slight ache on the right side of the lower back and then it got moved to my hip-deep in the socket like a toothache. I have had pain in my bones also for the past two days. Taking a hot water bath helped me and I was able to move around a little bi...  Read Full »

Dr. Rajiv Ranjan Kumar

Answer: Hi, Welcome to Based on your history, the common rheumatological condition that needs to be ruled out is spondyloarthritis (SPA). It includes many groups of diseases starting from ankylosing spondylitis, reactive arthritis, and others. It causes back pain, and lower limb arthritis and...  Read Full »

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