HomeAnswersDermatologyblistersWhat could cause itchy fluid-filled blisters on hands, legs, arms, and chest?

I have itchy, fluid-filled sores on my hands, legs, back, chest, and arms. Please help.

Share

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Vinodhini J.

Published At December 31, 2020
Reviewed AtAugust 29, 2023

Patient's Query

Hello doctor,

I am a 62-year-old male. I have worse skin conditions like hand sores, single sore on the legs, back, chest, and arms that itch. My hand sores tend to heal slowly but filled with fairly clear fluid. I have rash and lesions for approximately six months. I am currently on Mendocin and Allopurinol.

Hello,

Welcome to icliniq.com.

I understand your concern. But there are no attached photographs in your message. Kindly send the pictures of the affected areas to assess the condition and suggest you the appropriate diagnosis and treatment.

Patient's Query

Thank you doctor,

I have itchy spots on my arms, legs, and hands.

Hi,

Welcome back to icliniq.com.

Thanks for sharing the pictures (attachment removed to protect patient identity). I can think of two differentials. The first one is dermatitis herpetiformis, which is characterized by intense itching and fluid-filled lesions. Fluid-filled lesions are mainly over extensor, and due to intense itching, blisters usually gets ruptured, so intact blisters are not so common. Second is bullous pemphigoid, which is seen in the elderly and commonly over lower extremities, also has urticaria red patches and tense intact fluid-filled blisters. Are you on any treatment? Can you send me the biopsy or any other reports? Dapsone is the drug that can be effective in both conditions, though you will have to get a G6PD (Glucose-6-phosphate dehydrogenase) report for that.

Patient's Query

Thank you doctor,

I use Mupirocin ointment 2% for open sores, Clobetasol Propionate cream USP 0.05%, Betamethasone dipropionate ointment USP 0.05%, Hydroxyzine HCl 25 mg tablet for itching. I hope the files I am uploading are helpful.

Hi,

Welcome back to icliniq.com.

I think dermatitis herpetiformis and bullous pemphigoid as two probable diagnoses. I would have started Dapsone, maybe with a short course of oral corticosteroids. If it is not possible, Dapsone 100 mg would be my first-line treatment, along with the treatment you are already taking.

Patient's Query

Thank you doctor,

Should I give this information to my current dermatologist? Not sure what to do from here.

Hi,

Welcome back to icliniq.com.

A trial of Dapsone with topical Clobetasol and antihistamines should be the treatment plan. You can take the following medicines. Take Tablet Dapsone 100 mg once a day. Use Clobetasol propionate 0.05% cream twice a day, Cream Mupirocin twice a day and take Tablet Fexofenadine 180 mg twice a day for two weeks. Dapsone needs to be started after the G6PD investigation is normal.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Dilip Kumar Meena
Dr. Dilip Kumar Meena

Dermatology

Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Ask your health query to a doctor online

Dermatology

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy