Should I repeat a mammogram every 6 months at 47?

Question

Hello doctor,

I have recently been tested for BRCA1 and BRCA2 mutations and the results were negative. I had the testing done because my mom was diagnosed with breast cancer at the age of 51 and my maternal aunt had ovarian cancer. I was 47.I have been told by my gynaecologist that I need to get a mammogram every year but I don't know if that is enough screening for someone with my family history.

What are your thoughts on the idea of a mammogram every six months instead of once a year, for someone like me?I am also wondering if a negative genetic test really is a null finding for an increased cancer risk if there are many close relatives with a history of breast and ovarian cancer.Are there any other screening options like breast MRI that should be considered in addition to mammography for someone with my profile?

Please help.

Thank you for your guidance.

Answer 1

Hi,

Welcome to icliniq.com

I completely understand the stress and worry you may be going through, especially when cancer has touched more than one member of the family. However, I would like to reassure you about an important point: since your genetic testing was completed and came back negative, that is a very encouraging result.

Although your family history is concerning, negative BRCA1 and BRCA2 results dramatically minimize the risk of a hereditary cancer syndrome. In most circumstances, this means that your treatment and screening can adhere to conventional guidelines for women who do not have a known genetic mutation.

Screening for breast cancer with a mammogram every year is an appropriate and effective way to do so. Usually, once-a-year screening is enough to detect early changes. Six-monthly mammograms are not recommended as they offer little extra benefit and may subject women to unnecessary radiation exposure and anxiety.

Given your family history of ovarian cancer, annual pelvic ultrasound and CA-125 blood test are reasonable additions to your follow-up care. After that, no routine screening is required unless new symptoms or abnormalities develop.

The negative result of your genetic test is reassuring at this time, and no further screening is necessary. I hope this helps you to be clear and at peace.

I hope this addresses your concerns.

Please feel free to follow up if you need any additional clarification.

Thank you.