Carbidopa drug is given to people with Parkinson's disease to inhibit the peripheral metabolism of levodopa. It is a dopa decarboxylase inhibitor, and so it prevents the conversion of levodopa to dopamine. This property is significant because it allows a greater proportion of levodopa to cross the blood-brain barrier for the central nervous system effect.

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Will I get addicted to Clonazepam if I take it for more than two weeks?

Query: Hi doctor, I am a 72-year-old woman with Parkinson’s disease for six years. I take Carbidopa-Levodopa, Selegiline, and Rytary. I have a leg tremor from my hip to my toes. The medicine works well for the tremors, and I also have an internal tremor, which seems to be my central nervous system. ...  Read Full »

Dr. Gursimran Singh

Answer: Hi, Welcome to The medicines that you have been prescribed are perfectly fine. For internal tremors, Clonazepam is fine, but you have to keep on checking the addiction by reducing the dosage every other day. For 3 to 4 days, you have to take a full dose but keep on giving trials of th...  Read Full »

What is the treatment option for Parkinson's disease other than Levodopa?

Query: Hi doctor, I feel extreme fatigue in the morning. I have tremor and right leg tingling. I am experiencing brain fog, Parkinson like symptoms but I did not feel any improvement with Levodopa. My manganese levels are high. Please help.  Read Full »

Dr. Muhammad Majid Hanif

Answer: Hi, Welcome to I want to assure you that do not worry as everything is going to be fine soon. I have thoroughly gone through your case and can well understand your genuine concerns.  Read Full »

Will continuous intake of Carbidopa-Levodopa exacerbate hallucinations?

Query: I made mistake. Since carbidopa levodopa can precipitate or exacerbate hallucinations, i need to correct myself My wife takes 2 x 0.5 tabs 25/100 carbidopa daily.  Read Full »

Dr. Ashok Kumar

Answer: Thanks for using Icliniq. I do not understand what do you mean by 'I made mistake'. You are right in saying that carbidopa and levodopa combination may precipitate psychosis but it does not mean that it occurs in all. I also like to tell you that the studies have revealed that almost 40% of indivi...  Read Full »

Is there any alternative to Syndopa for treating Parkinson's disease?

Query: Hi doctor, My mother is having parkinson disease for the past 8 years. She is taking Syndopa 275 mg 3/4 five times a day, but still she is not feeling good. Any alternative?  Read Full »

Dr. Jaydeep Tripathy

Answer: Hello, Welcome to I understand your concern. Based on what stage of her disease she is in, there are quite a few alternatives available for parkinsonism. The first line of management is obviously the one that the doctor has given to you, Syndopa (a combination of Levodopa and Carbidop...  Read Full »

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