Is it advisable to use Prednisolone for long time after cataract surgery?

Q. Please explain the dosage of Prednisolone after cataract surgery.

Answered by
Dr. Vaibhev Mittal
and medically reviewed by Dr. Divya Banu M
This is a premium question & answer published on Nov 24, 2019 and last reviewed on: Jul 23, 2023

Hello doctor,

I am writing this to get your kind suggestion regarding my mother (Age: 56 years). Two years back, she had her cataract surgery for both eyes PCIOL. After having the surgery she was fine while she had these following drugs like Neopred, Xirom and Optimox. She was under these drops for one month but after stopping the use of those drops she was having severe eye pain with redness. So, we went to the doctor again and he prescribed Prednisolone eye drop for multiple times a day. But when she completes the dose of Prednisolone, then again she gets the same eye pain and redness. And the doctor again prescribed the same Prednisolone drop with high dose (every hour) but we know that Prednisolone is not good for long time use as it is steroid. So, in this circumstances I am seeking your kind suggestion on the above. Please suggest us what should we do.



Welcome to

Your mother has post operative uveitis which happens in some patients after cataract surgery. The treatment includes, we try to find out any cause for recurrent inflammation. If there is no cause then we treat the inflammation. If there is some inciting factor present (like IOL in sulcus irritating iris, vitreous loss, etc.), then we treat the cause. Only treatment available is steroids (best steroid is Prednisolone). If recurrent inflammation then we start with high dose and taper slowly. I would like to add Nepafenac eyedrop because recurrent inflammation may cause cystoid macular edema. Yes, you are right. Steroids if used for long time can cause glaucoma but do not worry. If patient is not sensitive to steroids then intraocular pressure will not increase in this short duration. Moreover, your surgeon will keep assessing pressure inside eye and will stop steroids if pressure increases. So, please do not worry and keep medication as per your surgeon instructions.

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