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Are new migraine injections like Aimovig or Ajovy effective?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have been experiencing migraines since college, but they have worsened lately. I feel a throbbing pain behind one eye, along with nausea, and sometimes light sensitivity that can last all day. I take Sumatriptan, but it only works about half the time.

My doctor mentioned new migraine injections like Aimovig or Ajovy. Do they really help that much? I experience eight to ten headache days a month, and it has begun to affect my work.

I have also noticed that red wine and lack of sleep trigger my migraines. Is it worth getting an MRI just to be safe? I am really tired of having to plan my life around my migraines.

Please guide.

Answered by Dr. Ahsanullah Niazai

Education:

MD

Professional Bio:

Dr. Ahsanullah Niazai is a General Physician with a strong commitment to patient-centered care and medical education. He is skilled in diagnosing and managing a wide range of acute and chronic health conditions. His areas of expertise include internal medicine, preventive healthcare, and clinical education, with a focus on promoting overall well-being and disease prevention.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I read your query and understand your concern.

I hear you, and it sounds incredibly frustrating to deal with migraines that interfere so much with your daily life and work.

Experiencing throbbing pain, nausea, and light sensitivity multiple times a month can make it feel like your schedule is completely controlled by your headaches, and it is completely understandable to feel exhausted by that.

The new migraine injections like Aimovig (Erenumab) and Ajovy (Fremanezumab), which target the calcitonin gene-related peptide (CGRP) pathway, have helped many people reduce both the frequency and severity of migraine attacks, especially for those who have not had consistent relief from oral medications like Sumatriptan.

Eight to ten headache days a month puts you in the category where preventive therapy is usually considered, and these injections could be an option worth discussing with your neurologist to see if you are a candidate.

Identifying and avoiding triggers such as red wine and sleep deprivation is helpful, but it often is not enough on its own, which is why preventive treatments can make a significant difference in quality of life.

As for imaging, an MRI (magnetic resonance imaging) is sometimes recommended if there are unusual features in your headache, such as sudden onset, changes in pattern, neurological symptoms, or if you or your doctor wants reassurance, but many people with a long history of typical migraines do not need one.

You deserve support and a treatment plan that allows you to feel more in control and less restricted by your migraines.

I hope I have addressed all your questions. If there is anything else, please let me know.

Thank you.

Medically reviewed by iCliniq medical review team
Published At January 9, 2026
Reviewed At January 12, 2026

Education:

MD

Professional Bio:

Dr. Ahsanullah Niazai is a General Physician with a strong commitment to patient-centered care and medical education. He is skilled in diagnosing and managing a wide range of acute and chronic health conditions. His areas of expertise include internal medicine, preventive healthcare, and clinical education, with a focus on promoting overall well-being and disease prevention.

This doctor is not available for online consultations on the platform anymore.

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Education:

MD

Professional Bio:

Dr. Ahsanullah Niazai is a General Physician with a strong commitment to patient-centered care and medical education. He is skilled in diagnosing and managing a wide range of acute and chronic health conditions. His areas of expertise include internal medicine, preventive healthcare, and clinical education, with a focus on promoting overall well-being and disease prevention.

This doctor is not available for online consultations on the platform anymore.

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