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HomeAnswersHematologycpk valueMy sister's CPK levels are elevated. Please help.

How can elevated levels of vitamin B12 levels be managed?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

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Published At August 25, 2018
Reviewed AtApril 24, 2024

Patient's Query

Hello doctor,

My sister’s blood report shows CPK was 290, which is on the higher side. So, the doctor advised checking B12 and it was found to be 185.3. What further investigation is required? She is 65 years old.


Welcome to icliniq.com.

CPK (creatine phosphokinase) is elevated when muscle injury occurs like in the case of myositis, muscle trauma, heart attack, etc. It had no relation with B12 level. Your CPK is only mildly elevated. Your B12 is definitely high for which following investigations can be done:

  1. SGOT, SGPT.
  2. Serum protein estimation.
  3. Serum urea, creatinine, eGFR (estimated glomerular filtration rate).
  4. Full CBC (complete blood count) with peripheral smear examination.

All these investigations will rule out liver disease, kidney disease, and blood abnormality, if present. These all can affect B12 level. According to reports, further comment can be given.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri


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