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How to manage depression and hyperthyroidism?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been suffering from depression for the past seven years and have been taking SSRIs and SNRIs for the last four years, but I have not seen any significant improvement. I also have low blood pressure, constant dizziness, and a fear of fainting in public. Additionally, I have hyperthyroidism and a fast metabolism, which makes it very difficult for me to gain weight and muscle. Despite my efforts, I remain underweight. Could you please advise me on how to manage these conditions together? What dietary, lifestyle, and medical adjustments can help me gain weight safely while also stabilizing my blood pressure and improving my mental health? Kindly suggest.

Answered by Dr. Georges Hany Kozah

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

Managing depression, low blood pressure, dizziness, hyperthyroidism, and weight gain challenges together requires a holistic approach that includes medical, dietary, and lifestyle adjustments. Here is a detailed plan to help stabilize your health.

Depression and medication adjustment: If SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotonin-norepinephrine reuptake inhibitors) have not helped in four years, it is time to talk to your psychiatrist about alternative treatments. Consider Bupropion (Wellbutrin) if you also experience fatigue and weight loss. Mirtazapine (Remeron) is another option that helps with depression and increases appetite and weight gain. TCA (tricyclic antidepressants) like Amitriptyline might be useful if SSRIs (selective serotonin reuptake inhibitors) do not work for you.

You can opt for therapies like CBT (cognitive behavioral therapy) or DBT (dialectical behavioral therapy). Medication alone may not be enough. Therapy can help manage depression symptoms, especially if dizziness and fainting are anxiety-related.

Low blood pressure and dizziness can be caused when hyperthyroidism speeds up metabolism and lowers blood pressure. SSRIs or SNRIs can sometimes cause dizziness as a side effect. For dehydration and low electrolytes (especially in summer), you can do the following:

  1. Increase salt intake: Add Himalayan salt to your water or meals (check with your doctor first). Electrolyte drinks like coconut water and ORS (oral rehydration salt) solutions are beneficial.

  2. Stay hydrated: Drink at least three liters of water daily (especially in summer). Avoid alcohol and caffeine as they worsen dehydration.

  3. Compression stockings: Helps blood circulation and prevents dizziness when standing up.

  4. Dizzy-proof your mornings: Get up slowly from bed. Try deep breathing before standing.

  5. Medications for low blood pressure: If severe, discuss with your doctor about Fludrocortisone or Midodrine, which help increase BP.

Hyperthyroidism and weight gain: Hyperthyroidism speeds up metabolism, making weight gain difficult. Balancing thyroid hormones is key. Diet and lifestyle changes to increase your weight are: Focus on calorie-dense but nutritious foods such as

  1. Healthy fats (avocado, nuts, olive oil, and peanut butter).

  2. Protein-rich foods (chicken, eggs, tofu, and Greek yogurt).

  3. Complex carbohydrates (oats, sweet potatoes, and brown rice).

  4. Eat six small meals per day instead of three large ones.

  5. Take smoothies and shakes: Blend full-fat yogurt, banana, peanut butter, honey, oats, and protein powder for a high-calorie drink.

  6. Strength training: Weightlifting helps build muscle and prevents excessive calorie burn. Avoid too much cardio, which can worsen weight loss.

  7. Check your thyroid medication: If you are on antithyroid medicines, your dosage may need adjustment if symptoms persist. If not on medications, discuss options with an endocrinologist.

Mental and physical energy boosters:

  1. Go outside early in the morning for 10 to 15 minutes of sunlight and vitamin D to improve mood and metabolism.

  2. Magnesium and B vitamins help with energy and nervous system health.

  3. Meditation and deep breathing can help control dizziness and anxiety.

Check with your doctor before changing your diet, lifestyle, and medicines.

I hope this helps you.

Thank you.

Medically reviewed by iCliniq medical review team
Published At May 29, 2025
Reviewed At June 4, 2025

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

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