iCliniq Logo
HomeAnswersPsychiatrydepression

I am 22. Can I switch to Bupropion or SNRI for my depression?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 22-year-old male struggling with depression, mainly experiencing low mood, lack of motivation, poor concentration, and difficulty sleeping. Over the past several months, I have tried two selective serotonin reuptake inhibitors (SSRIs), Fluoxetine and Sertraline, but did not notice significant improvement in my symptoms.

Would a different class of medication, such as Bupropion (an atypical antidepressant) or a serotonin-norepinephrine reuptake inhibitor (SNRI), be more appropriate for my current symptoms?

Additionally, how can I find a reliable cognitive behavioral therapy (CBT) therapist or support group near me?

Kindly help.

Hello,

Welcome to icliniq.com.

I have read your query and can understand your concern.

Since you have not experienced significant relief with two different selective serotonin reuptake inhibitors (SSRIs), it is appropriate to consider alternative medication options such as Bupropion (an atypical antidepressant) or a serotonin-norepinephrine reuptake inhibitor (SNRI) like Venlafaxine or Duloxetine.

Bupropion may be particularly helpful in your case because it tends to improve energy, motivation, and concentration. It is also less likely to cause sexual side effects or weight gain when compared to SSRIs. SNRIs may also be beneficial for individuals experiencing both mood-related and physical symptoms, such as fatigue or chronic pain.

Additionally, they can sometimes activate more than SSRIs. A psychiatrist can help evaluate your complete symptom profile and medical history to determine which treatment option is most suitable for you.

In addition to medication, cognitive behavioral therapy (CBT) has strong evidence for effectiveness in treating depression, mainly when used in combination with pharmacological treatment. To find a reliable CBT therapist or a support group near you, you can begin by asking your primary care provider or psychiatrist for a referral. You may also search directories or the official websites of national mental health organizations.

Many therapists and support groups now offer online sessions, which can provide ease and access. Engaging in both therapy and a personalized medication plan can significantly enhance your ability to manage depression and help you regain a sense of control and well-being.

I hope this helps.

Thank you.

Answered byDr. Ashraf Ghani

Medically reviewed byiCliniq medical review team

Published At October 12, 2025
Reviewed AtOctober 12, 2025

Same symptoms don't mean you have the same problem. Consult a doctor now!

Listen to related tracks in our music library

Ask your health query to a doctor online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.