Patient's Query
Hello doctor,
I am 27 and have been struggling with depression for about two years, but it has gotten much worse lately. I can barely get out of bed most days, and I have called in sick to work eight times this month. My apartment is a mess, I have not showered in four days, and I am living on takeout food. I started Sertraline six weeks ago, but I do not feel any better, and the side effects are terrible. I have no sex drive, gained 15 pounds, and feel emotionally numb all the time. My therapist wants to increase the dose, but I am worried it will make things worse. I had suicidal thoughts last week for the first time, and that really scared me. I have not told anyone because I do not want to be hospitalized and lose my job. My few remaining friends are getting tired of my canceling plans and negative attitude. I used to be outgoing and successful, but now I feel like a completely different person. I am worried this is permanent and will never feel normal again. Are there other medications that might work better? Should I try intensive therapy or maybe take medical leave from work? I desperately need help, but I do not know what steps to take next.
Please advise.
Hello,
Welcome to icliniq.com
I read your query and understand your concern.
What you are going through sounds deeply painful, but it is also something you do not have to face alone. Your symptoms, like exhaustion, isolation, emotional numbness, suicidal thoughts, and loss of motivation, are all signs of a serious depressive episode. But the good news is that this is treatable, and you can feel like yourself again with the right support.
Depression affects your motivation, thinking, energy, appetite, self-esteem, and relationships. What you are experiencing is not laziness, weakness, or personal failure; it is a medical condition.
Various treatment modalities:
Psychotherapy: Therapy helps you:
Understand root causes (trauma, thought patterns, beliefs).
Learn tools for managing mood, motivation, and relationships.
Reduce suicidal thoughts and build hope.
Your current therapist may be helpful, but if you are not improving, you might consider:
A different therapist with a stronger match (do not be afraid to switch).
Cognitive behavioral therapy (CBT): For thought and behavior change.
Dialectical behavioral therapy (DBT): If emotional regulation or self-harm is a concern.
Psychodynamic therapy: To understand deeper patterns and self-image.
Therapy, along with medication together is often more effective than either alone.
Medication: It is fine to switch, as you have been on Sertraline for six weeks and are experiencing:
No relief in mood.
Emotional numbness.
Weight gain.
No sex drive.
These are not side effects you should have to accept.
You may benefit more from a medication like:
Bupropion often boosts energy, libido, and motivation.
Duloxetine or Venlafaxine is especially helpful if physical pain or fatigue are also issues.
Mirtazapine is helpful for appetite and sleep, though it may cause weight gain.
Talk to your prescriber about changing medications and not increasing Sertraline if it is not working for you.
More support: If weekly therapy is not enough and your daily life is breaking down, you might need:
Intensive outpatient program (IOP): Therapy and support groups several times a week
Partial hospitalization (PHP): Day-long treatment without an overnight stay
Structured support that addresses medication, habits, social support, and emotional regulation
These programs are not for people who have “failed”; they are for people who need help recovering faster and more safely.
You have already missed eight days of work this month, your body is telling you it is time to stop and heal.
Ask your doctor or therapist to help you with documentation. Taking time off now could protect your job, your health, and your future.
Regarding your suicidal thoughts, you deserve support, not punishment. You do not have to be hospitalized just for having thoughts. But your therapist or doctor needs to know so they can help keep you safe.
Ask them to help you build a safety plan that includes:
Warning signs.
Coping strategies.
People to contact for 24/7 crisis support.
This is not the end, just the hardest chapter. Right now, you are not living, you are surviving. But this is not permanent. You can feel joy again, form new connections, and rediscover who you are. You are still you, just buried under illness, not lost. If you are looking for help, I would say to stay positive, even if depressed.
Hope this answers your query.
Thank you.
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Answered byDr. Saumya Mittal
Medically reviewed byiCliniq medical review team
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