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HomeAnswersPsychiatrydepressionI have been battling depression for the past 23 years and feel the medicines that I use are ineffective. Please help.

Which medications are best for chronic depression?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Manjunadh M

Medically reviewed by

iCliniq medical review team

Published At July 16, 2023
Reviewed AtJuly 16, 2023

Patient's Query

Hello doctor,

I have been battling with depression for the past 23 years, and I have been taking prescribed medications to manage my symptoms. Generally, when I take my medications, I feel alright. However, there are times when the medications do not seem to be as effective, and I suspect that this might be due to the quality of the drugs I am using. Currently, my medication regimen consists of tablet Flutop 20 mg capsule and 0.5 mg tablet Lonazep in the morning, and tablet Amicon 25 MG and 0.5 mg tablet Lonazep in the evening.

Therefore, I kindly request your advice on the same.

Answered by Dr. Manjunadh M


Welcome to Icliniq.com.

I read your query and can understand your concern.

I appreciate your concerns regarding depression, which can be a challenging condition to treat due to its fluctuating nature. It is important to note that even with highly effective antidepressants, the response rate is typically around 60 percent. The quality of medicines is standardized worldwide, so there should not be any significant differences in quality.

However, if you still have doubts about the quality of your medication, you may consider opting for medicines from well-known pharmaceutical companies. For example, the tablet Fludac (Fluoxetine) can be an alternative to the tablet Flutop (Fluoxetine). Additionally, it is worth noting that maintaining a healthy body weight through regular exercise, yoga, and weight reduction can potentially reduce the dosage requirement of medication and improve symptoms of depression.

I hope this advice is helpful to you.

If you have any further questions or concerns, please feel free to ask.

Thank you.

Patient's Query

Hello doctor,

Thank you for your response.

Given my extensive experience of over 20 years with these medications, I believe I can discern their quality. However, I understand that our opinions may differ regarding the overall quality of medicines. Considering this, I kindly request your recommendation as an alternative to the same generic. Additionally, I would greatly appreciate it if you could provide me with information on where these medications are available, including their shop addresses. Thank you. I eagerly await your reply.

Answered by Dr. Manjunadh M


Welcome to icliniq.com.

Glad to see you back. I am here to answer your health queries.

I suggest you can consider taking capsule Fludac (Fluoxetine) as an alternative to Flutop, and tablet Amitone (Amitriptyline) instead of tablet Amicon. These medications are widely available in most medical stores due to their popularity. Alternatively, you can also explore online stores to purchase these medications.

Best regards,

And please feel free to address any query here.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Manjunadh M
Dr. Manjunadh M


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