Dr. Sreejith. M. G
Diabetology
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Patient's Query
Hello doctor,
I am taking Enalapril 10 mg and developed psychosis with auditory hallucinations. Could it be due to my medication? It is listed as a rare side effect and the symptoms are worse when I take the medication and lessen when I stop taking it.
Hi,
Welcome to icliniq.com.
As you said ACE (angiotensin-converting enzyme) inhibitors usually will not produce any hallucination or psychosis but some rare reports of hallucinations are available which was mainly visual hallucination not auditory, but psychosis is unlikely. Anyway, you change Enalapril to some other antihypertensive tablets like calcium channel blockers or beta blockers and see the change. Consult a specialist doctor, discuss with them, and take medications with their consent.
If it is not improving with above medicine change, you have to evaluate further by getting a thyroid function test (hypo or hyperthyroidism), hemoglobin (Vitamin B12 deficiency anemia or iron deficiency) and calcium level with serum phosphorous (hyperparathyroidism- high calcium and parathyroid hormone). If above tests are normal, get an MRI (magnetic resonance imaging) of the brain and rule out any organic causes. If everything comes as normal, consult a neurologist or psychiatrist.
Patient's Query
Thank you doctor,
I am already with a psychiatrist and being treated with Olanzapine, but next appointment is two days later. It has been a holiday and I am curious so hence asking you. I have just noticed when I take Enalapril my symptoms are much worse. I forgot to take Enalapril this weekend and it was much better. It does say it can cause anxiety which I suffer from anyway. I also had been breastfeeding until recently. I am not saying there is not an underlying condition but I feel it is making it a lot worse.
Hi,
Welcome back to icliniq.com.
Yes, if you feel more problems after taking Enalapril, change it to some other antihypertensive, which I have already mentioned and see the change. Enalapril can cause hallucination. So change it.
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Diabetology
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