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How to manage erythema multiforme?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 20-year-old female who is 63 inches and 114 pounds. For several months, my health has been decreasing. At first, it was just migraines that lasted for hours to days in the front and temporal lobes and lack of sleep from troubling sleep. Later I had nosebleeds and easy bruising. As time went on, it was harder to have energy, and I lost 10 pounds.

I feel cold even if the weather is 212 Fahrenheit outside. My throat gets swollen, and it makes it hard to breathe and talk. My chest feels tight, and then I go into coughing fits. I have an autoimmune disorder called erythema multiforme, which gets triggered by cold sores, and I am allergic to the tablet Amoxicillin. I have taken over-the-counter medication for headaches, menstruation cramps, low-grade fevers, and antivirals for erythema multiforme five years back. What could this be? Please help.

Thank you.

Answered by Dr. Veerabhadrudu Kuncham

Education:

MBBS

Professional Bio:

Dr. Veerabhadrudu K is a highly qualified pediatrician and neonatologist. He specializes in diagnosing and treating a wide range of conditions in children, from common illnesses to complex medical concerns, with expertise and compassion. Dedicated to patient-centered care, he ensures children and families receive personalized, supportive guidance at every step.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

Autoimmune disorders occur when the immune system mistakenly attacks healthy cells and tissues in the body, leading to inflammation and various symptoms. Erythema multiforme (EM) is an immune-mediated skin condition that can be triggered by infections, medications, or other factors. Cold sores, also known as herpes labialis, are caused by the herpes simplex virus (HSV).

While cold sores are not typically considered an autoimmune disorder, they can potentially trigger or exacerbate autoimmune responses in susceptible individuals. In some cases, viral infections like HSV can induce or contribute to the development of autoimmune conditions. It is worth noting that erythema multiforme itself is not considered an autoimmune disorder, but it can sometimes be associated with underlying autoimmune conditions such as systemic lupus erythematosus (SLE) or autoimmune hepatitis.

If you have an autoimmune disorder like erythema multiforme triggered by cold sores, it is crucial to work closely with a healthcare professional, such as a dermatologist or rheumatologist, who can provide a proper diagnosis and develop an appropriate treatment plan. They may recommend medications to manage symptoms, such as antiviral medications for cold sores or immunosuppressive drugs for autoimmune conditions, depending on your specific situation.

Additionally, managing allergies is important to reduce the risk of triggering erythema multiforme or other immune-related reactions. Identifying and avoiding allergens, using antihistamines or other allergy medications as prescribed, and following good skincare practices can all help minimize the occurrence and severity of allergic reactions. Remember to seek professional medical advice to get a comprehensive understanding of your specific condition and appropriate management strategies.

I hope your query was resolved.

Please feel free to reach me again, in case of further queries.

Thank you.

Medically reviewed by iCliniq medical review team
Published At July 29, 2023
Reviewed At March 11, 2026

Education:

MBBS

Professional Bio:

Dr. Veerabhadrudu K is a highly qualified pediatrician and neonatologist. He specializes in diagnosing and treating a wide range of conditions in children, from common illnesses to complex medical concerns, with expertise and compassion. Dedicated to patient-centered care, he ensures children and families receive personalized, supportive guidance at every step.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Veerabhadrudu K is a highly qualified pediatrician and neonatologist. He specializes in diagnosing and treating a wide range of conditions in children, from common illnesses to complex medical concerns, with expertise and compassion. Dedicated to patient-centered care, he ensures children and families receive personalized, supportive guidance at every step.

This doctor is not available for online consultations on the platform anymore.

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