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How do I manage recurrent tender lesions on my shins?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have tender lesions on shins that come and go for years. Biopsy report suggests: Granulomatous inflammation composed of well-formed epitheloid-type granulomas with surround lymphocytes, histocytes, neutrophils, and eosinophils. Perivascular and mixed inflammation with the overlying dermis.

Yeast forms with focal budding within a granuloma. Mixed lobular and septal granulomatous panniculitis. My other test results: BUN 6 mg/dL, total bilirubin - 1.2 mg/dL, Angiotensin-1 converting enzyme - 70 U/L, monocytes, eosinophils, and basophils - 11, RBC - 5.26 cells/mcL.

Thank you.

Answered by Dr. Chaitra. P

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

I went through your history and medical reports. In my opinion, the details provided fit into a condition called erythema nodosum. However, there is a possibility of deep fungal infection of skin.

Erythema nodosum is a condition, wherein there occurs a reaction in the fat tissue beneath your skin. The reason for such a reaction could be many but is clearly not known. Major ones would be an infection anywhere else in the body. Intake of oral contraceptive pills or a few other medications in the past, history of tuberculosis, sometimes pregnancy, and so on.

Symptoms occur in a repeating fashion and seen commonly in young women. You may also have a fever during the episode.

The investigations to do are a tissue fungal culture to rule out a fungal pathology, chest x-ray, serum ASLO (antistreptolysin O) titer, complete blood counts, liver function tests, etc. It depends on clinical evaluation.

You may require taking systemic steroids and other immunosuppressive medications after confirmation of diagnosis. With treatment, the condition usually remits but recurrence depends on the identification of the underlying cause and its treatment. It requires a thorough clinical and systemic examination to rule out the causes along with prescription-based immunosuppressive medications under medical monitoring.

Preventive measures include avoid acute physical stress. Timely treatment of other routine illnesses have a role in preventing repeated attacks.

Thank you

Answered byDr. Chaitra. P

Medically reviewed byDr. Hemalatha

Published At December 5, 2019
Reviewed AtMarch 9, 2026

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