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What causes vomiting on the first dose of malaria medicine?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My son (2 years 8 months) was hospitalized due to fever along with a sand paper kind of rashes in the body for four days. He was suspected of dengue and the initial blood test showed IgG positive. Herewith I am attaching the discharge summary and all other reports. After getting discharged, he was completely active for two days. He was on antibiotic Ziprax for four days. Again, fever started and went up to 103 degrees Fahrenheit. The doctor has given malaria medicine. We like to get your opinion on this. My son vomited the first dose of the new medicine and I am afraid to give more doses. Other than fever, he is completely normal and his activity level is good.

Answered by Dr. Faisal Abdul Karim Malim

Education:

MBBS

Professional Bio:

Dr. Faisal Abdul Karim Malim is a compassionate Pediatrician dedicated to providing specialized care for infants, children, and adolescents. He focuses on managing childhood illnesses, promoting growth and development, and guiding parents on preventive healthcare practices. With his expertise in pediatrics, Dr. Malim ensures child-friendly consultations and comprehensive treatment plans to support the overall health and well-being of young patients.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

1. Children vomit after giving malaria medication (Chloroquine). If the child has vomited the medicine immediately after consumption that dose is missed. Hence, it should be repeated.

2. I suggest syrup Emeset (Ondansetron) half an hour before giving the medication. It will help to some extent. However, if the child still vomits even with Emeset, then it becomes important to admit the child and give intravenous medication after proving it is a case of malaria.

3. Your reports (attachment removed to protect patient identity) are suggestive of a high level of chronic infection or inflammation as ESR is high (erythrocyte sedimentation rate).

4. The white blood cell count (WBC count) is also high. This can be possible if the child was infected with a bacterial infection whilst the child was having dengue already (immunity is low in dengue).

5. Since the child has gone through so much, the child will definitely require more time to get back to normal. And, the child is susceptible to infection till the child has not become normal. Also, the weather conditions play a part.

6. I would advice to continue the same medicines which are currently going on. Please give P250 (Paracetamol) once every 6 hourly for three days.

7. If fever still persists more than three days or the child becomes toxic at any point of time, then it is advisable to show physically to your nearest doctor and evaluate completely with blood tests and if required admit.

Patient's Query

Thank you doctor,

So, can I continue the same medication?

Answered by Dr. Faisal Abdul Karim Malim

Education:

MBBS

Professional Bio:

Dr. Faisal Abdul Karim Malim is a compassionate Pediatrician dedicated to providing specialized care for infants, children, and adolescents. He focuses on managing childhood illnesses, promoting growth and development, and guiding parents on preventive healthcare practices. With his expertise in pediatrics, Dr. Malim ensures child-friendly consultations and comprehensive treatment plans to support the overall health and well-being of young patients.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

Yes, you can.

Medically reviewed by iCliniq medical review team
Published At December 20, 2016
Reviewed At June 22, 2026

Education:

MBBS

Professional Bio:

Dr. Faisal Abdul Karim Malim is a compassionate Pediatrician dedicated to providing specialized care for infants, children, and adolescents. He focuses on managing childhood illnesses, promoting growth and development, and guiding parents on preventive healthcare practices. With his expertise in pediatrics, Dr. Malim ensures child-friendly consultations and comprehensive treatment plans to support the overall health and well-being of young patients.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Faisal Abdul Karim Malim is a compassionate Pediatrician dedicated to providing specialized care for infants, children, and adolescents. He focuses on managing childhood illnesses, promoting growth and development, and guiding parents on preventive healthcare practices. With his expertise in pediatrics, Dr. Malim ensures child-friendly consultations and comprehensive treatment plans to support the overall health and well-being of young patients.

This doctor is not available for online consultations on the platform anymore.

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