Patient's Query
Hi doctor,
I am experiencing frequent urination at night, resulting in waking up multiple times to use the bathroom. What could be the reason?
I really appreciate any help you can provide.
Please guide.
Hi,
Welcome to icliniq.com.
I understand your concerns.
Any other symptoms? Can you elaborate further?
Please feel free to follow up with the answer.
Thank you.
Patient's Query
Hi doctor,
Thank you for your reply.
I stopped taking Solfenaicin two days ago, and my urine returned to normal. However, after a week, I noticed that my daytime urine output decreased while my nighttime output increased, causing me to wake up more frequently.
My urine output seems to fluctuate daily; some days I have more output during the day and less at night, while on other days it’s the opposite. I am not sure what is happening.
I completed a uroflowmetry test, a KUB (kidneys, ureters, and bladder) scan with post-void residual (PVR), and had my creatinine levels and urine analyzed. Everything came back normal, except for urine sugar, which was positive due to the SGLT2 (sodium-glucose cotransporter 2) inhibitor medication.
I showed the results to my local GP, who suggested that the SGLT2 inhibitor was not the right medication for me. I stopped taking it a week ago, but my urine issues have remained the same.
Please advise me on what to do next.
Hi,
Welcome back to icliniq.com.
I understand your concerns.
Based on your symptoms and the reports you shared, it does not appear that you are experiencing kidney failure or a dangerous blockage. Your normal creatinine levels, uroflowmetry results, KUB (kidney, ureters, and bladder) scan with post-void residual measurements, and urine analysis are all reassuring indicators.
The SGLT2 (sodium-glucose cotransporter 2) inhibitor is likely the primary reason for these fluctuations. These medications cause excess sugar to be excreted in the urine, and when the urine sugar level becomes significantly high, the body pulls more water into the urine along with it. This commonly results in increased urination, nighttime frequency, dehydration-like symptoms, and variable urine output from day to day.
Even after stopping the medication, the bladder can remain temporarily sensitive before returning to normal. Additionally, when someone becomes overly focused on urine volume, normal fluctuations may start to feel much more pronounced.
For now, I recommend the following:
Maintain normal hydration during the daytime and avoid intentionally reducing your water intake.
Avoid caffeine and excessive fluids in the evening, particularly tea, coffee, or soft drinks.
Do not monitor your urine volume or frequency every few hours, as this can increase bladder awareness and anxiety.
Continue to monitor your blood sugar levels carefully after stopping the SGLT2 medication.
At this time, it seems that you are experiencing bladder sensitivity and changes in fluid balance, rather than a serious urinary tract issue.
I hope you find this information helpful. If you have any further questions, feel free to reach out.
Thank you.
Was this conversation helpful?
Answered byDr. Mudasir Ahmad Jamali
Medically reviewed byiCliniq medical review team
Same symptoms don't mean you have the same problem. Consult a doctor now!
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.
