Dr. Goswami Parth Rajendragiri
Pathology
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Patient's Query
Hello doctor,
The last few days my wife says that she feels sick. After that, I took my wife to the doctor. She suggested a few tests named HB electrophoresis, ferritin, TSH, PPBS, USG lower abdomen, CBC, PBF and urine test.
Result:Hb%: 10.2, platelet-266000, RBC-4.28, WBC-7300, MCV-74, HCT/PCV-32%, TSH: 4.39, normal urine, pus cell: 1-2, epithelial cell: 1-3, PPBS- 5.9, USG- normal, S. ferritin: 10.98 ng/ml, HB electerophoresis: Hb A- 71.3, Hb E-25.3, HbA2 - 3.4.
Doctor comments: Blood disorder, Hemoglobin E trait.
Kindly explain the report. As far as I know, HbE trait patient generally has higher ferritin level but in my wife, it is lower than normal. I am afraid about my 1-year-old baby boy and next baby and generation. Please suggest to me.
Hi,
Welcome to icliniq.com.
The serum ferritin level is not high in every case of hemolytic anemia. Your electrophoresis report is suggestive of HbE (attachment removed to protect patient identity). It is a case of a mild form of hemolytic anemia. In that case, the ferritin level might not be raised. Along with low ferritin, your red blood cells count is also low. Usually, in hemoglobinopathy, red blood cells count is high. So your wife's complete diagnosis is HbE trait with secondary iron deficiency anemia. So you can give your wife Iron tablets to raise the hemoglobin level and ferritin level.
HbE is not a major hemolytic disease, so you need not worry about your child or future child although your child acquires HbE trait. HbE trait patient lives a normal life. I strongly recommend you to get investigated for hemoglobinopathy by electrophoresis because if you have trait then your child can acquire HbE disease. So revert back with your electrophoresis report as well.
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Pathology
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