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Which new therapies can help manage my HR- breast cancer at 52?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 52 years old and dealing with HR (hormone receptor)-negative breast cancer. The surgery and radiation have taken a toll on me, and I am scared because I know this type of cancer can be harder to treat. I need to know if there are any newer medications or therapies that could give me a better chance. If there is anything more that can be done,

I would really appreciate your advice.

Thank you.

Hello,

Welcome to icliniq.com.

I can understand your concern.

HR (hormone receptor)-negative tumors, a type of breast cancer that does not have estrogen or progesterone receptors, are a bit more aggressive. However, they tend to respond well to chemotherapy. If these tumors are also HER2 (human epidermal growth factor receptor 2)-negative, they may benefit from adding immunotherapy, specifically Pembrolizumab, to chemotherapy.

On the other hand, if they are HER2-positive, adding anti-HER2 therapy, such as Trastuzumab and Pertuzumab, to chemotherapy could be beneficial. Carboplatin can also be added to the usual chemotherapy drugs, as some studies have shown it provides an advantage in treating HR-negative tumors.

I hope this helps.

Thank you.

Medically reviewed byiCliniq medical review team

Published At September 24, 2024
Reviewed AtJune 4, 2026

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