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Q. What do very high levels of vitamin B12 indicate?

Answered by
Dr. Goswami Parth Rajendragiri
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Mar 18, 2023

Hello doctor,

I felt pins and needles in my legs and arms, so the doctor advised three tests for sugar, calcium, and vitamin B12. Sugar and calcium were normal, but my vitamin B12 was greater than 2000 pg/mL. I do not take any supplements. Is it due to pernicious anemia? Please help.

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Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

You need to investigate further with the following investigations to rule out any hematological abnormality or liver or kidney disease if present.

1. Full CBC (complete blood count) with peripheral smear examination.

2. SGPT (serum glutamic-pyruvic transaminase) and SGOT (serum glutamic-oxaloacetic transaminase).

3. Serum urea and creatinine estimation.

I suggest you consult a physician for examination. You attach these reports so I can guide you further. Also, in pernicious anemia, B12 deficiency occurs, not excess B12.

Hope this will help you.

Thanks and take care.


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