High Vitamin B12

An increased level of vitamin B12 in blood ranges above 900 pg/ml. This indicates the presence of renal dysfunctions, liver disorders, diabetes, and leukemia. High doses of vitamin B12 can cause dermatologic conditions like acne and rosacea, which produces pus and redness. The excess vitamin is stored in the liver, and when not consumed it takes about three to five years to exhaust the stored vitamins.

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I have a high vitamin B12 value and a family history of the JAK2 mutation, blood disorders, and cancer. Kindly help.

Query: Hello doctor, I am a 54-year-old female. My vitamin B12 was 2000 this week. I do not take any supplements. I also have hypopituitarism, and I do not know if it is related. I have a strong genetic predisposition to develop JAK2 (Janus kinase) and blood disorders. I have lost five pounds in three week...  Read Full »


Dr. Singh Smrita

Answer: Hello, Welcome to icliniq.com. Increased vitamin B12 levels in the absence of supplementation can be seen in liver disease and myeloproliferative disorders like polycythemia vera. I suggest you have liver function tests and a hemogram done initially. If your liver function tests are normal and your ...  Read Full »

What can cause my serum B12 levels to be so high?

Query: Hello doctor, I am hypertensive and asthmatic. I got my routine blood tests done. I found that my serum B12 is 1103. Is it ok? Currently, I am taking Telma AM, Supradyn, and Foracort 40 mg.  Read Full »


Dr. Manzoor Ahmad Parry

Answer: Hello, Welcome to icliniq.com. I have seen your query. You have raised B12 levels, which can be due to the Supradyn tablet (which is vitamin B12). So I would suggest stopping vitamin B12.  Read Full »

What is the reason for having raised vitamin B12 and SGOT?

Query: Hi doctor, I am 33 years old male. I have a B12 level of 1800 pg/mL and SGOT of 80 U/L. My SGOT level is within range. I have never taken B12 supplements. Please suggest.  Read Full »


Dr. Lohit Chauhan

Answer: Hi, Welcome to icliniq.com. Do not be scared. Repeat the tests soon. A raised B12 can happen due to laboratory error. Even after that, if you have SGOT (aspartate transaminase) above SGPT (alanine transaminase), you should do a USG (ultrasound) abdomen. A raised SGOT above SGPT of about 2:1 ra...  Read Full »

What is the reason for decreased T4 and increased TSH levels in blood?

Query: Hello doctor, I got a blood test done recently. In the reports, which I have attached, most of my results are fine, but some major concerns are my vitamin B12 level is 1477 ng/mL, T4 is 3.8, TSH is 12.63, and platelet count is 140. Is something wrong going on in my body? Are these indicating some ...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. I have seen your reports (attachment removed to protect patient identity). Your T4 level is low, and TSH (thyroid stimulating hormone) is high, it suggests primary hypothyroidism. For which, I suggest Levothyroxine 25 or 50 mcg daily. You also have vitamin D deficiency, ...  Read Full »

What causes an elevated vitamin B12 level without the use of supplements?

Query: Hello doctor, I had pain in my right lower back following playing basketball. I consulted a physiotherapist, and he suggested me do some blood work for inflammatory markers, and the results were normal. I also did complete blood count (CBC), liver function test (LFT), kidney function, cholesterol, ...  Read Full »


Dr. Nupoor Acharya

Answer: Hello, Welcome to icliniq.com. Elevated vitamin B12 levels can be seen in certain blood-related conditions like myeloproliferative disorders. It may also be seen in some liver conditions. Since all the remaining values are normal, these conditions seem unlikely in your case. However, to be sur...  Read Full »

Why do I have increased vitamin B12 levels along with high MCV, MCH, and MCHV?

Query: Hi doctor, I have high MCV, MCH, and MCHV. I also have high B12 levels. What does this mean? I have stomach upset, diarrhea and I pass stool after every meal within an hour. My stool seems to be yellow or orange-brown in color. I have a past history of food intolerance and allergy. Currently, I a...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. Following is my opinion for your asked question. In the attached report (attachment removed to protect patient identity), MCV (mean corpuscular volume), MCH (mean corpuscular hemoglobin), and MCHC (mean corpuscular hemoglobin concentration) is in high range within borde...  Read Full »

What does my blood test reports suggest?

Query: Hi doctor, Can you please review my blood and urine test? My concern are a low level of ferritin, a high level of B12, and my urine WBC is very high.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Following is my opinion on your asked question. The low ferritin, Low Mcv (microcytic anemia), could be suggestive of early iron deficiency anemia. The common cause for high B12 includes supplement intake, liver disease, or kidney disease. Your liver and kidney profi...  Read Full »

How much vitamin B12 is safe while pregnant?

Query: Hi doctor, I am a 34 years old female, and I am ten weeks, four days pregnant. I am a vegetarian, and before I was pregnant, I would intermittently take a vitamin B12 supplement. I found the bottle two weeks ago, and without thinking about it, I started taking it daily in addition to my prenatal vi...  Read Full »


Dr. J N Naidu

Answer: Hi, Welcome to icliniq.com. Oral absorption of vitamin B12 is a complex process and all the vitamins taken orally are not completely absorbed. You mentioned that you took the tablet intermittently and did not mention the exact frequency. Most studies are on patients taking high doses of vitamin B1...  Read Full »

How can I reduce my vitamin B12 level to help my sleep cycle?

Query: Hello doctor, I was taking a supplement with alpha lipoic acid, carnosine, and B complex. On 19th May, I started having problems with sleeping, and the duration was much shorter or fragmented. I stopped taking the supplement on 21st May. Blood tests showed that B12 levels were high at 1430. Folic ...  Read Full »


Dr. Kaushal Bhavsar

Answer: Hello, Welcome to icliniq.com. I can understand your concern. I have gone through the reports you have attached (attachment removed to protect patient identity). Since it is not in English, I do not understand completely but somehow I manage to understand the reports. All are normal. Yes, you ...  Read Full »

Why do I get elevated levels of vitamin B12 and testosterone?

Query: Hello doctor, I am a 43-year-old female. I take 20 mg Trintellex, as well as bio-identical progesterone, testosterone, DHEA, and thyroid. I take a sublingual methyl B-12 as well as zinc, P5P, magnesium, Vitamin D, Glutathione and Borage oil. I received bloodworm back today with troubling results...  Read Full »


Dr. Sadaf Mustafa

Answer: Hi, Welcome to icliniq.com. I do understand that your blood levels of both make and female hormones are elevated but most likely they are due to exogenous consumption. I was wondering as to why were you taking these hormones?  Read Full »

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