High Vitamin B12

An increased level of vitamin B12 in blood ranges above 900 pg/ml. This indicates the presence of renal dysfunctions, liver disorders, diabetes, and leukemia. High doses of vitamin B12 can cause dermatologic conditions like acne and rosacea, which produces pus and redness. The excess vitamin is stored in the liver, and when not consumed it takes about three to five years to exhaust the stored vitamins.

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My laboratory test report suggests an increase in vitamin B12 levels, and I also experience blurry vision, sour mouth, and backbone pain. Why?

Query: Hello doctor, I recently got my laboratory test done for vitamin B12. The levels are increased. My LFT tests were normal. I also have blurry vision, a sour mouth, and backbone pain. What is your first advice? What additional tests are needed? Please help.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I went through your query and understood your concern. Usually, myeloproliferative neoplasms, kidney diseases, and liver diseases are some of the causes of high vitamin B12 (cobalamin) levels. If you have taken supplements containing vitamin B12, then your B12 can be h...  Read Full »

The test I underwent for the pricking sensation in my arms and legs showed very high vitamin B12. Does it indicate pernicious anemia?

Query: Hello doctor, I felt pins and needles in my legs and arms, so the doctor advised three tests for sugar, calcium, and vitamin B12. Sugar and calcium were normal, but my vitamin B12 was greater than 2000 pg/mL. I do not take any supplements. Is it due to pernicious anemia? Please help.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. You need to investigate further with the following investigations to rule out any hematological abnormality or liver or kidney disease if present. 1. Full CBC (complete blood count) with peripheral smear examinatio...  Read Full »

My mother is healthy, but her blood report suggests that her vitamin B12 levels are high. Why?

Query: Hello doctor, My mom is 73 years old and is active for her age. We recently got some tests done for her, some of them are a blood sugar test, liver function test, kidney function test, and lipid profile. All reports turned normal except for the vitamin B12 test, which is higher than normal. Her B12...  Read Full »

Dr. Archana

Answer: Hello, Welcome to icliniq.com. I read your query and understand your concern. Kindly get a peripheral smear for your mother to know if she has megaloblastic anemia. Usually, high levels of vitamin B12 cause polycythemia vera, joint pains, and generalized body pains. If she is having a complete bl...  Read Full »

Vitamin B12 level is high in a diabetic patient. Please help.

Query: Hello doctor, I am 60, weight is 44 kg, height is 5.6, diabetes for past 25 years, on low carbohydrate diet for 80 days, taking no medicine for diabetes now. Sugar levels are under control, checking every day. The problem from past 50 days is that there are feet and ankle swelling that disappears i...  Read Full »

Dr. Noushif. M

Answer: Hi, Welcome to icliniq.com. High vitamin B12 can result from multiple causes. Since your liver function test, kidney function test, peripheral blood smear, etc., are normal (attachment removed to protect patient identity), we can rule out these as the cause. Other causes like diabetes (which you h...  Read Full »

My blood test report shows elevated vitamin B12 levels, which contradicts what I expected. Please help.

Query: Hi doctor, I had all symptoms of vitamin B12 deficiency and have been on medications like tablet Esomeprazole, Omeprazole, and Pantoprazole for the last 16 years. So requested a test. The fasting test result shows 1522 pg/ml for vitamin B12 serum, a complete opposite of what I had expected. So I too...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I have reviewed your query, and here is my advice. Your main concern is regarding the high vitamin B12 level. Let me know if even a single supplement of vitamin B12 can increase your vitamin B12 level. You have been using the supplement for ten days. So that is the r...  Read Full »

What can be the cause for high B12 level in a person with MTHFR mutation?

Query: Hello doctor, I have genetic mutation MTHFR. I am on thyroid for hypothyroidism. My B12 level is 1476, the normal range is between 138 to 652 pmol/L. How can I lower my B12 level? Is this level a cause for concern? All the other blood levels are normal other than WBC which is at 3.4 and neutrophils...  Read Full »

Dr. Elina Angelova Beleva

Answer: Hello, Welcome to icliniq.com. It is essential to know the primary reason for vitamin B12 testing. Was it done due to any complaints that could be related to anemia like fatigue, malaise, or any other symptoms that could be related to thrombotic complications possibly due to the inherited MTHFR (me...  Read Full »

My daughter has high vitamin B12 levels after taking vitamin B12 supplement drops. Why?

Query: Hello doctor, Last year, we did an annual checkup for my daughter and found that her vitamin B12 levels were very low. The doctor prescribed vitamin drops and asked her to continue. A few days back, we had her annual blood checkup, and her vitamin B12 levels were high (around 2000 ng/mL). What coul...  Read Full »

Dr. Prakash Chandra Girdhar Lal Nagar

Answer: Hello, Welcome to icliniq.com. I read your query and understand your concern. Her vitamin B12 levels are too high. The very first thing is to stop the supplement. One should not depend on one isolated laboratory report, so check the vitamin B12 level again. If the repeated level is also high, I sugg...  Read Full »

My vitamin B12 is high. How can I lower it?

Query: Hi doctor, As I took master health blood test and in the result, my vitamin B12 is high. How can I lower it? I am afraid of this. Please help me.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Kindly provide me any other clinical complaint if you have. Kindly mention whether you have taken any vitamin B12 supplement or tablet or injection? Attach your all reports to give more comment. Usually, liver disease, kidney disease, B12 intake, myeloproliferative n...  Read Full »

My vitamin B12 level is elevated. Is it dangerous as I have been taking vitamin B12 supplements for many years?

Query: Hi doctor, I got my complete blood count done, and there is an elevated level of vitamin B12. I have taken vitamin B12 supplements on and off for many years. Is it dangerous?  Read Full »

Dr. Sugreev Singh

Answer: Hi, Welcome to icliniq.com. I understand your concern. From the reports attached (attachment removed to protect the patient's identity), it is not dangerous, so do not worry at all. However, you should stop taking vitamin B12 supplements because you already have a good amount of vitamin B12 in yo...  Read Full »

What can be done to reduce high vitamin B12 level?

Query: Hello doctor, I have been taking Vitamin B medication for over one year and my Vitamin B12 level is very high, greater than 2000. What should I do to reduce the level? I am 27 years female. Please advise.  Read Full »

Dr. Divakara. P

Answer: Hi, Welcome to icliniq.com. Vitamin B12 is a water-soluble vitamin. It means any excess of Vitamin B12 in the body shall be flushed out in urine. So just stop taking further vitamin supplements and the B12 level shall normalize. You can repeat the test after one month.  Read Full »

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